This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
LIN9 Polyclonal Antibody
catalog :
PA5-43640
quantity :
100 uL
price :
US 454.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
citations: 2
Reference
Roberts M, Sahni J, Schrock M, Piemonte K, Weber Bonk K, Seachrist D, et al. LIN9 and NEK2 Are Core Regulators of Mitotic Fidelity That Can Be Therapeutically Targeted to Overcome Taxane Resistance. Cancer Res. 2020;80:1693-1706 pubmed publisher
Sahni J, Gayle S, Webb B, Weber Bonk K, Seachrist D, Singh S, et al. Mitotic Vulnerability in Triple-Negative Breast Cancer Associated with LIN9 Is Targetable with BET Inhibitors. Cancer Res. 2017;77:5395-5408 pubmed publisher
product information
Product Type :
Antibody
Product Name :
LIN9 Polyclonal Antibody
Catalog # :
PA5-43640
Quantity :
100 uL
Price :
US 454.00
Clonality :
Polyclonal
Purity :
Affinity Chromatography
Host :
Rabbit
Reactivity :
Human
Applications :
Western Blot: 0.2-1 ug/mL
Species :
Human
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
LIN9 belongs to the lin-9 family and acts as a tumor suppressor. It inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. LIN9 plays a role in the expression of genes required for the G1/S transition.
Immunogen :
Synthetic peptide directed towards the N-terminal of human LIN9 (aa 35-84).
Format :
Liquid
Applications w/Dilutions :
Western Blot: 0.2-1 ug/mL
Aliases :
2700022J23Rik; BARA; BARPsv; Beta subunit-associated regulator of apoptosis; HuLin-9; LIN9; Lin-9; lin-9 DREAM MuvB core complex component; lin-9 homolog; lin-9 homolog (C. elegans); mLin-9; pRB-associated protein; protein lin-9 homolog; rb related pathway actor; TGS; TGS1; TGS2; TUDOR gene similar 1 protein; TUDOR gene similar protein; Type I interferon receptor beta chain-associated protein
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA