This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
eIF3h Polyclonal Antibody
catalog :
PA5-43574
quantity :
100 uL
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry
product information
Product Type :
Antibody
Product Name :
eIF3h Polyclonal Antibody
Catalog # :
PA5-43574
Quantity :
100 uL
Price :
US 464.00
Clonality :
Polyclonal
Purity :
Affinity Chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Immunocytochemistry: 1:500, Immunohistochemistry: 1:500, Western Blot: 0.2-2 ug/mL
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
eIF3H is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
Immunogen :
Synthetic peptide directed towards the N-terminal of human EIF3H (aa 1-50).
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:500, Immunohistochemistry: 1:500, Western Blot: 0.2-2 ug/mL
Aliases :
1110008A16Rik; 40 kDa; 40kD; 9430017H16Rik; eIF-3 gamma; eIF3 p40 subunit; eIF3 p40 subunit {ECO:0000255; eIF-3-gamma; eIF3-gamma; EIF3H; eIF3h {ECO:0000255; eIF3p40; eIF3-p40; EIF3S3; eukaryotic translation initiation factor 3 subunit 3; eukaryotic translation initiation factor 3 subunit 3 {ECO:0000255; eukaryotic translation initiation factor 3 subunit 3 gamma; eukaryotic translation initiation factor 3 subunit H; eukaryotic translation initiation factor 3 subunit H {ECO:0000255; eukaryotic translation initiation factor 3 subunit H-like protein; eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD); eukaryotic translation initiation factor 3, subunit 3 (gamma); eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD); eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa; eukaryotic translation initiation factor 3, subunit H; eukaryotic translation initiation factor subunit H-like protein; HAMAP-Rule:MF_03007}; MGC102958
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA