This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PLEKHO1 Polyclonal Antibody
catalog :
PA5-43108
quantity :
100 uL
price :
US 481.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
product information
Product Type :
Antibody
Product Name :
PLEKHO1 Polyclonal Antibody
Catalog # :
PA5-43108
Quantity :
100 uL
Price :
US 481.00
Clonality :
Polyclonal
Purity :
Affinity Chromatography
Host :
Rabbit
Reactivity :
Human
Applications :
Western Blot: 0.2-1 ug/mL
Species :
Human
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
CKIP1 was identified through a yeast-two hybrid screening as a protein that would interact with only one of the two catalytic subunits of the casein kinase 2 complex. CKIP1 is a pleckstrin homology domain-containing protein localized within the nucleus and at the plasma membrane that interacts with CK2alpha but not CK2alpha', and is thought to play a role in targeting CK2alpha to a particular cellular location. CKIP1 has been implicated in muscle differentiation and the regulation of cell morphology and actin cytoskeleton. CKIP1 can also interact with other proteins such as ATM, an upstream kinase of p53, and recruit the nuclear ATM to the plasma membrane, suggesting CKIP1 may regulate ATM function through re-localizing ATM. CKIP1 can also form a complex with the kinase AKT, leading to a down-regulation of PI3K/AKT signaling and suppression of tumor growth in vivo.
Immunogen :
Synthetic peptide directed towards the N-terminal of human PLEKHO1 (aa 1-50).
Format :
Liquid
Applications w/Dilutions :
Western Blot: 0.2-1 ug/mL
Aliases :
2810052M02Rik; Casein kinase 2-interacting protein 1; C-Jun-binding protein; CK2 interacting protein 1; CK2 interacting protein 1; HQ0024c protein; CK2-interacting protein 1; CKIP1; CKIP-1; HQ0024c; HQ0024c protein; JBP; Jun zipper-associated 2; Jza2; JZA-20; OC120; Osteoclast maturation-associated gene 120 protein; PH domain-containing family O member 1; pleckstrin homology domain containing O1; pleckstrin homology domain containing, family O member 1; pleckstrin homology domain-containing family O member 1; pleckstrin homology domain-containing family O member 1-like; PLEKHO1; RGD1311487; RP11-458I7.3; TNF intracellular domain-interacting protein
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA