ACSL3 Polyclonal Antibody | Invitrogen PA5-42883 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ACSL3 Polyclonal Antibody

catalog :

PA5-42883

quantity :

100 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunocytochemistry

citations: 4

Reference
DiNatale A, Worrede A, Iqbal W, Marchioli M, Toth A, Sj xf6 str xf6 m M, et al. IL-1β expression driven by androgen receptor absence or inactivation promotes prostate cancer bone metastasis. Cancer Res Commun. 2022;2:1545-1557 pubmed publisher
Fernández L, Merino M, Colmenarejo G, Moreno Rubio J, Sánchez Martínez R, Quijada Freire A, et al. Metabolic enzyme ACSL3 is a prognostic biomarker and correlates with anticancer effectiveness of statins in non-small cell lung cancer. Mol Oncol. 2020;14:3135-3152 pubmed publisher
Ndiaye H, Liu J, Hall A, Minogue S, Morgan M, Waugh M. Immunohistochemical staining reveals differential expression of ACSL3 and ACSL4 in hepatocellular carcinoma and hepatic gastrointestinal metastases. Biosci Rep. 2020;40: pubmed publisher
Jung H, Shimizu Albergine M, Shen X, Kramer F, Shao D, Vivekanandan Giri A, et al. TNF-α induces acyl-CoA synthetase 3 to promote lipid droplet formation in human endothelial cells. J Lipid Res. 2019;: pubmed publisher

product information

Product Type :

Antibody

Product Name :

ACSL3 Polyclonal Antibody

Catalog # :

PA5-42883

Quantity :

100 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 1:200, Western Blot: 0.2-1 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

An initial reaction in fatty acid metabolism in eukaryotic cells is activation of fatty acids catalyzed by acyl-CoA synthetase. FACL3 (fatty acid CoA ligase, long-chain 3) is identified as member of the acyl-CoA synthetase (ACS) family by PCR of rat brain cDNAs using primers based on the conserved region of the ACS protein. The 720-amino acid rat protein preferentially utilizes myristate, laurate, arachidonate, and eicosapentaenoate, and is expressed primarily in brain. The predicted 720-amino acid FACL3 human protein is 92% identical to that of rat.

Immunogen :

Synthetic peptide directed towards the N-terminal of human ACSL3 (aa 74-123).

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:200, Western Blot: 0.2-1 ug/mL

Aliases :

2610510B12Rik; Acs3; Acsl3; acyl-CoA synthetase long chain family member 3; acyl-CoA synthetase long-chain family member 3; Arachidonate--CoA ligase; Brain acyl-CoA synthetase II; C85929; FACL3; fatty acid Coenzyme A ligase, long chain 3; fatty-acid-Coenzyme A ligase, long-chain 3; LACS 3; LACS3; lignoceroyl-CoA synthase; long-chain acyl-CoA synthetase 3; Long-chain-fatty-acid--CoA ligase 3; Pro2194