SGPP2 Polyclonal Antibody | Invitrogen PA5-42767 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SGPP2 Polyclonal Antibody

catalog :

PA5-42767

quantity :

100 uL

price :

US 460.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

citations: 2

Reference
Mart xed n Hern xe1 ndez D, Mart xed nez M, Robledo Monta xf1 a J, Mu xf1 oz L xf3 pez M, Virto L, Ambrosio N, et al. Neuroinflammation related to the blood-brain barrier and sphingosine-1-phosphate in a pre-clinical model of periodontal diseases and depression in rats. J Clin Periodontol. 2023;50:642-656 pubmed publisher
Dowdy T, Zhang L, Celiku O, Movva S, Lita A, Ruiz Rodado V, et al. Sphingolipid Pathway as a Source of Vulnerability in IDH1mut Glioma. Cancers (Basel). 2020;12: pubmed publisher

product information

Product Type :

Antibody

Product Name :

SGPP2 Polyclonal Antibody

Catalog # :

PA5-42767

Quantity :

100 uL

Price :

US 460.00

Clonality :

Polyclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry: 5 ug/mL, Western Blot: 2 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Sphingosine 1-phosphate (S1P) is a highly bioactive lipid that has a myriad of biological effects both intracellularly as a second messenger and extracellularly by binding to the S1P(1-5)/Gprotein- coupled receptors of the endothelial differentiation gene family. Intracellularly, at least two enzymes, sphingosine kinase (1 and 2) and S1P phosphatase, regulate the activity of S1P by governing the phosphorylation of S1P. SPPase2 is localized to the endoplasmic reticulum. The enzymatic activity and localization of SPPase2 are similar to SPPase1. The tissue expression of SPPase2 was different from that of SPPase1. SPPase2 is an important member of the SPPase family whichplay a role in attenuating intracellular S1P signaling.

Immunogen :

Synthetic peptide directed towards the C-terminal of human SGPP2 (aa 301-350).

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: 5 ug/mL, Western Blot: 2 ug/mL

Aliases :

FLJ39004; RGD1565739; SGPP2; sphingosine 1-phosphate phosphohydrolase 2; sphingosine-1-phosphatase 2; Sphingosine-1-phosphate phosphatase 2; sphingosine-1-phosphate phosphotase 2; Spp2; SPPase2