Plasma Kallikrein Polyclonal Antibody | Invitrogen PA5-42752 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Plasma Kallikrein Polyclonal Antibody

catalog :

PA5-42752

quantity :

100 µL

price :

US 464

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

Product Type :

Antibody

Product Name :

Plasma Kallikrein Polyclonal Antibody

Catalog # :

PA5-42752

Quantity :

100 µL

Price :

US 464

Clonality :

Polyclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Western Blot: 2.5 µg/mL

Species :

Human

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.

Immunogen :

Synthetic peptide directed towards the middle region of human KLKB1

Format :

Liquid

Applications w/Dilutions :

Western Blot: 2.5 µg/mL

Aliases :

antigen, prostate specific; APS; EC 3.4.21.34; Fletcher factor; Kal3; Kal-3; kallikrein; kallikrein 3, plasma; kallikrein B plasma; kallikrein B, plasma (Fletcher factor) 1; kallikrein B, plasma 1; kallikrein B1; Kalp1; KALP15; kininogenin; Klk3; KLKB1; Pk; PKK; PKKD; plasma kallikrein; Plasma kallikrein heavy chain; Plasma kallikrein light chain; Plasma prekallikrein; PPK; prekallikrein; PSA