DEGS1 Polyclonal Antibody | Invitrogen PA5-42741 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

DEGS1 Polyclonal Antibody

catalog :

PA5-42741

quantity :

100 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 3

Reference
Iino Y, Naganuma T, Arita M. Dysregulated ceramide metabolism in mouse progressive dermatitis resulting from constitutive activation of Jak1. J Lipid Res. 2023;64:100329 pubmed publisher
James J, Zemskova M, Eccles C, Varghese M, Niihori M, Barker N, et al. Single Mutation in the NFU1 Gene Metabolically Reprograms Pulmonary Artery Smooth Muscle Cells. Arterioscler Thromb Vasc Biol. 2021;41:734-754 pubmed publisher
Boulter E, Estrach S, Tissot F, Hennrich M, Tosello L, Cailleteau L, et al. Cell metabolism regulates integrin mechanosensing via an SLC3A2-dependent sphingolipid biosynthesis pathway. Nat Commun. 2018;9:4862 pubmed publisher

product information

Product Type :

Antibody

Product Name :

DEGS1 Polyclonal Antibody

Catalog # :

PA5-42741

Quantity :

100 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:200, Western Blot: 0.2-1 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The product of the DEGS1 gene is a member of the membrane fatty acid (sphingolipid delta 4 ) desaturase family. Reported to function by inserting double bonds at delta 4 position in fatty acids. DEGS1 is an intracellular enzyme. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulation biosynthetic processing of the EGF receptor. Two splice variants have been identified.

Immunogen :

Synthetic peptide directed towards the N-terminal of human DEGS1 (aa 2-51).

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:200, Western Blot: 0.2-1 ug/mL

Aliases :

AA536663; Cell migration-inducing gene 15 protein; Degenerative spermatocyte homolog 1; degenerative spermatocyte homolog 1 (Drosophila); degenerative spermatocyte homolog 1, lipid desaturase; degenerative spermatocyte homolog, lipid desaturase; degenerative spermatocyte-like protein RDES; Degs; DEGS1; DEGS-1; delta 4-desaturase, sphingolipid 1; Delta(4)-desaturase; delta(4)-desaturase, sphingolipid 1; DES1; Des-1; dihydroceramide desaturase; dihydroceramide desaturase 1; dihydroceramide desaturase-1; DSH1; FADS7; fb81d06; hypothetical protein LOC507290; im:6909319; Mdes; membrane fatty acid (lipid) desaturase; membrane lipid desaturase; MGC5079; MIG15; migration-inducing gene 15 protein; MLD; sphingolipid 1; sphingolipid delta 4 desaturase; sphingolipid delta(4)-desaturase 1; sphingolipid delta(4)-desaturase DES1; wu:fa25h01; wu:fb81d06