NEU1 Polyclonal Antibody | Invitrogen PA5-42552 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NEU1 Polyclonal Antibody

catalog :

PA5-42552

quantity :

100 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

citations: 5

Reference
Sesorova I, Sesorov V, Soloviev P, Lakunin K, Dimov I, Mironov A. Role of Endothelial Regeneration and Overloading of Enterocytes with Lipids in Capturing of Lipoproteins by Basement Membrane of Rat Aortic Endothelium. Biomedicines. 2022;10: pubmed publisher
Karmakar J, Mandal C. Interplay Between Sialic Acids, Siglec-E, and Neu1 Regulates MyD88- and TRIF-Dependent Pathways for TLR4-Activation During Leishmania donovani Infection. Front Immunol. 2021;12:626110 pubmed publisher
Song Z, Xu Y, Zhang L, Zhou L, Zhang Y, Han Y, et al. Comprehensive Proteomic Profiling of Urinary Exosomes and Identification of Potential Non-invasive Early Biomarkers of Alzheimer's Disease in 5XFAD Mouse Model. Front Genet. 2020;11:565479 pubmed publisher
Lillehoj E, Guang W, Hyun S, Liu A, Hegerle N, Simon R, et al. Neuraminidase 1-mediated desialylation of the mucin 1 ectodomain releases a decoy receptor that protects against Pseudomonas aeruginosa lung infection. J Biol Chem. 2019;294:662-678 pubmed publisher
Diao Y, Fang R, Li B, Meng Z, Yu J, Qiu Y, et al. A tiling-deletion-based genetic screen for cis-regulatory element identification in mammalian cells. Nat Methods. 2017;14:629-635 pubmed publisher

product information

Product Type :

Antibody

Product Name :

NEU1 Polyclonal Antibody

Catalog # :

PA5-42552

Quantity :

100 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry: 5 ug/mL, Western Blot: 5 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

NEU1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A. Mutations in NEU1 gene can lead to sialidosis.The protein encoded by this gene encodes the lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis.

Immunogen :

Synthetic peptide directed towards the middle region of human NEU1

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: 5 ug/mL, Western Blot: 5 ug/mL

Aliases :

AA407268; AA407316; Acetylneuraminyl hydrolase; Aglp; Apl; Bat7; Bat-7; EC 3.2.1.18; exo-alpha-sialidase; FLJ93471; G9; G9 sialidase; HLA-B-associated transcript 7; lysosomal sialidase; Map-2; N-acetyl-alpha-neuraminidase 1; NANH; Neu; NEU1; Neu-1; neuraminidase 1; neuraminidase 1 (lysosomal sialidase); SIAL1; sialidase 1; sialidase 1 (lysosomal sialidase); sialidase-1