SLC26A5 Polyclonal Antibody | Invitrogen PA5-42533 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SLC26A5 Polyclonal Antibody

catalog :

PA5-42533

quantity :

100 µL

price :

US 446

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

citations: 1

Reference
Harrison M, Driscoll B, Farnsworth J, Hinton A, Peppi M, McLean W, et al. Automated Western Blot Analysis of Ototoxin-Induced Prestin Burst in the Blood after Cyclodextrin Exposure. Otol Neurotol. 2023;44:e653-e659 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SLC26A5 Polyclonal Antibody

Catalog # :

PA5-42533

Quantity :

100 µL

Price :

US 446

Clonality :

Polyclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry: 5 µg/mL, Western Blot: 2.5 µg/mL

Species :

Human

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

SLC26A5 is a member of the SLC26A/SulP transporter family. SLC26A5 is specifically expressed in outer hair cells (OHCs) of the cochlea and is essential in auditory processing. Intracellular anions are thought to act as extrinsic voltage sensors, which bind to this protein and trigger the conformational changes required for rapid length changes in OHCs. Mutations in its gene have been associated with non-syndromic hearing loss.This gene is a member of the SLC26A/SulP transporter family. It encodes a protein that is specifically expressed in outer hair cells (OHCs) of the cochlea and is essential in auditory processing. Intracellular anions are thought to act as extrinsic voltage sensors, which bind to this protein and trigger the conformational changes required for rapid length changes in OHCs. Mutations in this gene have been associated with non-syndromic hearing loss. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Immunogen :

Synthetic peptide directed towards the middle region of human SLC26A5

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: 5 µg/mL, Western Blot: 2.5 µg/mL

Aliases :

DFNB61; MGC118886; MGC118887; MGC118888; MGC118889; outer hair cell motor protein; PRES; Prestin; prestin (motor protein); Slc26a5; solute carrier family 26 (anion exchanger), member 5; solute carrier family 26 member 5; solute carrier family 26, member 5; solute carrier family 26, member 5 (prestin); solute carrier family 26, member 5 (prestin) isoform 1; solute carrier family 26, member 5 (prestin) isoform 2