product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PEMT Polyclonal Antibody
catalog :
PA5-42383
quantity :
100 uL
price :
US 474.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot
more info or order :
citations: 4
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig s3d, s3e
Kumar A, Sundaram K, Mu J, Dryden G, Sriwastva M, Lei C, et al. High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance. Nat Commun. 2021;12:213 pubmed publisher
Dave N, Judd J, Decker A, Winslow W, Sarette P, Villarreal Espinosa O, et al. Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks. Aging Cell. 2023;22:e13775 pubmed publisher
Christensen K, Malysheva O, Carlin S, Matias F, MacFarlane A, Jacobs R, et al. Mild Choline Deficiency and MTHFD1 Synthetase Deficiency Interact to Increase Incidence of Developmental Delays and Defects in Mice. Nutrients. 2021;14: pubmed publisher
Kim Y, Seok S, Byun S, Kong B, Zhang Y, Guo G, et al. AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle. Nat Commun. 2018;9:540 pubmed publisher
product information
Product Type :
Antibody
Product Name :
PEMT Polyclonal Antibody
Catalog # :
PA5-42383
Quantity :
100 uL
Price :
US 474.00
Clonality :
Polyclonal
Purity :
Affinity Chromatography
Host :
Rabbit
Reactivity :
Human, Rat
Applications :
Surface plasmon resonance: Assay-dependent, Western Blot: 0.2-1ug/mL
Species :
Human, Rat
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. The protein localizes to the endoplasmic reticulum and mitochondria-associated membranes. The gene is within the Smith-Magenis syndrome region on chromosome 17. Alternate splicing of this gene results in three transcript variants encoding two different isoforms.
Immunogen :
Synthetic peptide directed towards the C-terminal of human PEMT (aa 152-199).
Format :
Liquid
Applications w/Dilutions :
Surface plasmon resonance: Assay-dependent, Western Blot: 0.2-1ug/mL
Aliases :
MGC2483; PEAMT; PEMPT; Pempt2; PEMT; PEMT2; PHOMETH; phosphatidylethanolamine N-methyltransferase; phosphatidylethanolamine N-methyltransferase-like protein; phospholipid methyltransferase; PLMT; PNMT; similar to phosphatidylethanolamine N-methyltransferase; zgc:55479
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA