PCSK5 Polyclonal Antibody | Invitrogen PA5-42378 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PCSK5 Polyclonal Antibody

catalog :

PA5-42378

quantity :

100 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

citations: 2

Reference
Saeki K, Qiu W, Friedman R, Pan S, Lu J, Ichimiya S, et al. Inactivation of Notch4 Attenuated Pancreatic Tumorigenesis in Mice. Cancer Res Commun. 2022;2:1601-1616 pubmed publisher
Li J, Liu J, Lupino K, Liu X, Zhang L, Pei L. Growth Differentiation Factor 15 Maturation Requires Proteolytic Cleavage by PCSK3, -5, and -6. Mol Cell Biol. 2018;38: pubmed publisher

product information

Product Type :

Antibody

Product Name :

PCSK5 Polyclonal Antibody

Catalog # :

PA5-42378

Quantity :

100 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Western Blot: 0.2-1 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

PCSK5 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. PCSK5 mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known. The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known.

Immunogen :

Synthetic peptide directed towards the middle region of human PCSK5

Format :

Liquid

Applications w/Dilutions :

Western Blot: 0.2-1 ug/mL

Aliases :

b2b1549Clo; b2b585Clo; PC5; PC5/6A; PC5A; PC6; PC6A; PCSK5; prohormone convertase 5; proprotein convertase 5; Proprotein convertase 6; proprotein convertase PC5; proprotein convertase subtilisin/kexin type 5; protease PC6; rPC5; SPC6; subtilase; Subtilisin/kexin-like protease PC5; subtilisin-like proprotein convertase 6