product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
FAH Polyclonal Antibody
catalog :
PA5-42049
quantity :
100 uL
price :
US 514.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, pigs
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section, western blot knockout validation, immunohistochemistry knockout validation
more info or order :
citations: 5
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; pigs ; loading ...; fig 1h
  • western blot knockout validation; pigs ; 1:200; loading ...; fig 1g
Gu P, Yang Q, Chen B, Bie Y, Liu W, Tian Y, et al. Genetically blocking HPD via CRISPR-Cas9 protects against lethal liver injury in a pig model of tyrosinemia type I. Mol Ther Methods Clin Dev. 2021;21:530-547 pubmed publisher
Imre G, Tak xe1 cs B, Czipa E, Drubi A, Jaksa G, Latinovics D, et al. Prolonged activity of the transposase helper may raise safety concerns during DNA transposon-based gene therapy. Mol Ther Methods Clin Dev. 2023;29:145-159 pubmed publisher
Chi H, Gan C, Jiang Y, Chen D, Qiu J, Yang Q, et al. The compound heterozygous mutations of c.607G>a and c.657delC in the FAH gene are associated with renal damage with hereditary tyrosinemia type 1 (HT1). Mol Genet Genomic Med. 2023;11:e2090 pubmed publisher
Kopasz A, Pusztai D, Karkas R, Hudoba L, Abdullah K, Imre G, et al. A versatile transposon-based technology to generate loss- and gain-of-function phenotypes in the mouse liver. BMC Biol. 2022;20:74 pubmed publisher
Ming G, Guo W, Cheng Y, Wang J. Identification and evaluation of fructose-bisphosphate aldolase B as a potential diagnostic biomarker in choledochal cysts patients: a quantitative proteomic analysis. Transl Pediatr. 2021;10:2083-2094 pubmed publisher
product information
Product Type :
Antibody
Product Name :
FAH Polyclonal Antibody
Catalog # :
PA5-42049
Quantity :
100 uL
Price :
US 514.00
Clonality :
Polyclonal
Purity :
Affinity Chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Immunohistochemistry (Paraffin): 1:400, Immunohistochemistry: Assay-Dependent, Western Blot: 0.2-1 ug/mL
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
This gene encodes the last enzyme in the tyrosine catabolism pathway. FAH deficiency is associated with Type 1 hereditary tyrosinemia (HT).
Immunogen :
Synthetic peptide directed towards the N-terminal of human FAH (aa 2-51).
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:400, Immunohistochemistry: Assay-Dependent, Western Blot: 0.2-1 ug/mL
Aliases :
Beta-diketonase; FAA; FAH; fb59b12; fumarylacetoacetase; Fumarylacetoacetate hydrolase; fumarylacetoacetate hydrolase (fumarylacetoacetase); LOW QUALITY PROTEIN: fumarylacetoacetase; wu:fb59b12; zgc:55316
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA