C4BPA Polyclonal Antibody | Invitrogen PA5-42001 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

C4BPA Polyclonal Antibody

catalog :

PA5-42001

quantity :

100 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

citations: 2

Reference
Sharma S, Bhatnagar R, Gaur D. Bacillus anthracis Poly-γ-D-Glutamate Capsule Inhibits Opsonic Phagocytosis by Impeding Complement Activation. Front Immunol. 2020;11:462 pubmed publisher
Thomson J, Plecha S, Krukonis E. Ail provides multiple mechanisms of serum resistance to Yersinia pestis. Mol Microbiol. 2019;111:82-95 pubmed publisher

product information

Product Type :

Antibody

Product Name :

C4BPA Polyclonal Antibody

Catalog # :

PA5-42001

Quantity :

100 uL

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Western Blot: 0.2-1 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

There are 3 variants of Complement component 4 binding protein (C4bp), which is composed of alpha and beta chains. The predominant form is a 570 kDa complex of 7 alpha chains and 1 beta chain. The other complexes formed are a 530 kDa homoheptamer of alpha chains or a 500 kDa complex of 6 alpha chains and 1 beta chain. C4bp regulates the activation of the classical complement pathway. It is a cofactor to the C3b/C4b inactivator, crucial to the proteolytic cleavage of C4b and important in cleavage of C3b. C4bp also regulates the C4bC2a complex (C3 convertase), accelerating its degradation by dissociating the complement fragment C2a. Both the C4bp alpha and beta chains interact with anticoagulant protein S and C4bp alpha binds protein S. C4bp is expressed in the blood serum.

Immunogen :

Synthetic peptide directed towards the middle region of human C4BPA

Format :

Liquid

Applications w/Dilutions :

Western Blot: 0.2-1 ug/mL

Aliases :

AI195242; C4b-binding protein; C4b-binding protein alpha chain; C4bp; C4bpa; complement component 4 binding protein; complement component 4 binding protein alpha; complement component 4 binding protein, alpha; proline-rich protein; PRP; RP11-164O23.4