KChIP2 Polyclonal Antibody | Invitrogen PA5-41075 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

KChIP2 Polyclonal Antibody

catalog :

PA5-41075

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry

citations: 2

Reference
Jiang X, Yang F, Ou D, Huang L, Li H, Lang M. MCC950 ameliorates ventricular arrhythmia vulnerability induced by heart failure. Bioengineered. 2022;13:8593-8604 pubmed publisher
Borghetti G, Eisenberg C, Signore S, Sorrentino A, Kaur K, Alejandro Andrade A, et al. Notch Signaling Modulates the Electrical Behavior of Cardiomyocytes. Am J Physiol Heart Circ Physiol. 2017;:ajpheart.00587.2016 pubmed publisher

product information

Product Type :

Antibody

Product Name :

KChIP2 Polyclonal Antibody

Catalog # :

PA5-41075

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunohistochemistry: 5 ug/mL, Western Blot: 0.06 ug/mL

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Voltage-gated potassium (Kv) channels are key components of the potassium currents in the heart and central nervous system. In the heart, Kv4 channels are involved in the repolarization phase of the action potential. In the brain however, these channels prevent reverse-propagation of action potentials. Found associated with Kv4 channels are a group of calcium-binding proteins termed KChIPs (Kv channel interacting proteins). KChIPs are small molecular weight proteins that bind to the cytoplasmic amino termini of Kv4 alpha-subunits and help to modulate its function. There are currently three known KChIPs; KChIP1 expressed in the brain; KChIP2 expressed in the brain, heart, and lung, and has three isoforms, a, b, and c; and KChIP3, also known as calsenilin and DREAM (downstream regulatory elements (DRE)-antagonist modulator) which is expressed in the brain and testis.

Immunogen :

Synthetic peptide directed towards the N-terminal of human KCNIP2

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: 5 ug/mL, Western Blot: 0.06 ug/mL

Aliases :

A-type potassium channel modulatory protein 2; Cardiac voltage-gated potassium channel modulatory subunit; DKFZp566L1246; KCHIP2; KChlP2; Kcnip2; Kv channel interacting protein 2; Kv channel-interacting protein; Kv channel-interacting protein 2; MGC17241; potassium channel auxiliary subunit KCHIP2; potassium channel-interacting protein 2; potassium voltage-gated channel interacting protein 2; si:ch73-173h19.2