TRPV4 Polyclonal Antibody | Invitrogen PA5-41066 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TRPV4 Polyclonal Antibody

catalog :

PA5-41066

quantity :

100 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, immunohistochemistry

citations: 2

Reference
Manneck D, Braun H, Schrapers K, Stumpff F. TRPV3 and TRPV4 as candidate proteins for intestinal ammonium absorption. Acta Physiol (Oxf). 2021;233:e13694 pubmed publisher
Wang S, He H, Long J, Sui X, Yang J, Lin G, et al. TRPV4 Regulates Soman-Induced Status Epilepticus and Secondary Brain Injury via NMDA Receptor and NLRP3 Inflammasome. Neurosci Bull. 2021;37:905-920 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TRPV4 Polyclonal Antibody

Catalog # :

PA5-41066

Quantity :

100 uL

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human, Rat

Applications :

Immunohistochemistry: Assay-Dependent, Western Blot: 0.2-1 ug/mL

Species :

Human, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

TRPV4 (Transient Receptor Potential Cation Channel Subfamily V Member 4) is a cation-selective channel, activated in response to systemic osmotic pressure. Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. TRPV4 is a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The TRPV4 protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in the TRPV4 gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Diseases associated with TRPV4 include Metatropic Dysplasia and Spondylometaphyseal Dysplasia, Kozlowski Type. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen :

Synthetic peptide directed towards the middle region of human TRPV4

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: Assay-Dependent, Western Blot: 0.2-1 ug/mL

Aliases :

0610033B08Rik; BCYM3; CMT2C; HMSN2C; LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily V member 4; OSM9-like transient receptor potential channel 4; osm-9-like TRP channel 4; osmosensitive transient receptor potential channel 4; Otrpc4; SMAL; SPSMA; SSQTL1; Transient receptor potential cation channel subfamily V member 4; transient receptor potential cation channel, subfamily 5, member 4; transient receptor potential cation channel, subfamily V, member 4; transient receptor potential protein 12; Trp12; Trpv4; trpv4 channel; Vanilloi; vanilloid receptor-like channel 2; Vanilloid receptor-like protein 2; vanilloid receptor-related osmotically activated channel; vanilloid receptor-related osmotically activated channel (Vroac); vanilloid receptor-related osmotically activated channel protein; vanilloid receptor-related osmotically-activated channel; Vrl2; VRL-2; VROAC; VR-OAC; wu:fp52e02