SUV420H1 Polyclonal Antibody | Invitrogen PA5-40926 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SUV420H1 Polyclonal Antibody

catalog :

PA5-40926

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Maksimova V, Popova V, Prus A, Lylova E, Usalka O, Sagitova G, et al. Insights into the Mechanism of Curaxin CBL0137 Epigenetic Activity: The Induction of DNA Demethylation and the Suppression of BET Family Proteins. Int J Mol Sci. 2023;24: pubmed publisher

product information

Product Type :

Antibody

Product Name :

SUV420H1 Polyclonal Antibody

Catalog # :

PA5-40926

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 4-8 ug/mL, Surface plasmon resonance: Assay-dependent, Western Blot: 0.2-2 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2). Plays a role in myogenesis by regulating the expression of target genes, such as EID3.

Immunogen :

Synthetic peptide directed towards the middle region of human SUV420H1

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 4-8 ug/mL, Surface plasmon resonance: Assay-dependent, Western Blot: 0.2-2 ug/mL

Aliases :

[histone H4]-lysine20 N-methyltransferase KMT5B; [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B; AA117471; C630029K18Rik; CGI85; CGI-85; histone-lysine N-methyltransferase KMT5B; histone-lysine N-methyltransferase SUV420H1; Kmt5b; lysine (K)-specific methyltransferase 5B; lysine methyltransferase 5B; lysine N-methyltransferase 5B; Lysine-specific methyltransferase 5B; MGC118906; MGC118909; MGC21161; MGC703; si:dkey-12e7.2; Su(var)4-20 homolog 1; suppressor of variegation 4-20 homolog 1; suppressor of variegation 4-20 homolog 1 (Drosophila); suppressor of variegation 4-20 protein-like 1; SUV420; SUV420H1; suv4-20h1; Unknown (protein for MGC:137299); wu:fb97g06; wu:fi57g03; zgc:103527