IkB beta Polyclonal Antibody | Invitrogen PA5-40909 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IkB beta Polyclonal Antibody

catalog :

PA5-40909

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

citations: 1

Reference
Tong M, Yi L, Sun N, Cheng Y, Cao Z, Wang J, et al. Quantitative Analysis of Cellular Proteome Alterations in CDV-Infected Mink Lung Epithelial Cells. Front Microbiol. 2017;8:2564 pubmed publisher

product information

Product Type :

Antibody

Product Name :

IkB beta Polyclonal Antibody

Catalog # :

PA5-40909

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry: 5 ug/mL, Western Blot: 5 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The NF-kB/Rel transcription factors are present in the cytosol in an inactive state, complexed with the inhibitory IkB proteins. Most agents that activate NF-kB do so through a common pathway based on phosphorylation-induced, proteasome-mediated degradation of IkB. The key regulatory step in this pathway involves activation of a high molecular weight IkB kinase (IKK) complex whose catalysis is generally carried out by three tightly associated IKK subunits. IKK alpha and IKK beta serve as the catalytic subunits of the kinase and IKK gamma serves as the regulatory subunit. Activation of IKK depends upon phosphorylation at Ser177 and Ser181 in the activation loop of IKK beta (Ser176 and Ser180 in IKK alpha), which causes conformational changes, resulting in kinase activation.

Immunogen :

Synthetic peptide directed towards the C-terminal of human NFKBIB (aa 282-331).

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: 5 ug/mL, Western Blot: 5 ug/mL

Aliases :

I kappa B beta; I(Kappa)B(beta); ikappaBbeta; I-kappa-B-beta; IkB; IKB B; IKB beta; Ikbb; ikB-B; IkBbeta; ikB-beta; NF kappa BIB; NF-kappa-B inhibitor beta; NF-kappa-BIB; NFKB inhibitor beta; NFKBIB; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, beta; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta; Thyroid receptor; thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP 9; TRIP9; TRIP-9