MED17 Polyclonal Antibody | Invitrogen PA5-40839 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MED17 Polyclonal Antibody

catalog :

PA5-40839

quantity :

100 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
chromatin immunoprecipitation; mouse; loading ...; fig 4g immunoprecipitation; mouse; loading ...; fig 4a chromatin immunoprecipitation; human; loading ...; fig 4g, 4h immunoprecipitation; human; loading ...; fig 4b, 8d	Vaughan C, Singh S, Subler M, Windle J, Inoue K, Fry E, et al. The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment of PLK3. Nat Commun. 2021;12:704 pubmed publisher

product information

Product Type :

Antibody

Product Name :

MED17 Polyclonal Antibody

Catalog # :

PA5-40839

Quantity :

100 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

ChIP Assay: 0.5 ug, Immunohistochemistry (Paraffin): 4-8 ug/mL, Western Blot: 0.2-1 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e. g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

Immunogen :

Synthetic peptide directed towards the N-terminal of human CRSP6 (aa 156-205).

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 0.5 ug, Immunohistochemistry (Paraffin): 4-8 ug/mL, Western Blot: 0.2-1 ug/mL

Aliases :

77kDa; activator-recruited cofactor 77 kDa component; ARC77; C330002H14Rik; cofactor required for Sp1 transcriptional activation subunit 6; cofactor required for Sp1 transcriptional activation, subunit 6; cofactor required for Sp1 transcriptional activation, subunit 6 (77kD); cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa; CRSP complex subunit 6; CRSP6; CRSP77; DRIP77; DRIP80; Med17; Mediator complex subunit 17; mediator of RNA polymerase II transcription subunit 17; Thyroid hormone receptor-associated protein complex 80 kDa component; transcriptional coactivator CRSP77; Trap80; Vitamin D3 receptor-interacting protein complex 80 kDa component

more info or order :

Invitrogen product webpage