KIF3A Polyclonal Antibody | Invitrogen PA5-40805 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

KIF3A Polyclonal Antibody

catalog :

PA5-40805

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

Product Type :

Antibody

Product Name :

KIF3A Polyclonal Antibody

Catalog # :

PA5-40805

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Western Blot: 0.2-1 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The kinesins constitute a large family of microtubule-dependent motor proteins which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. Members of the heterotrimeric kinesin II family of microtubule associated motors generally contain two different motor subunits from the KIF3 family, which includes KIF3A, B and C. KIF3 isoforms mediate anterograde transport of membrane bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and the Golgi, and transport of protein complexes within cilia and flagella required for their morphogenesis. KIF3A may influence neurogenesis at the level of embryonic cellular events, where the asymmetry of the genetic control circuit controlling left-right (L-R) axis determination is defined. Loss of KIF3A function in mice photoreceptors causes apoptotic cell death, suggesting that kinesin II mediated transport is required for proper cell fate.

Immunogen :

Synthetic peptide directed towards the C-terminal of human KIF3A (aa 634-683).

Format :

Liquid

Applications w/Dilutions :

Western Blot: 0.2-1 ug/mL

Aliases :

fc55h04; FLA10; hypothetical protein LOC550267; Kif3; KIF3A; Kifl; kinesin family member 3a; kinesin family protein 3A; kinesin-II subunit; kinesin-like protein KIF3A; Kinesin-like protein KIF3A-like protein; KLP-20; Kns3; microtubule plus end-directed kinesin motor 3A; N-4 kinesin; Unknown (protein for IMAGE:7984856); wu:fc55h04; zgc:110284; zgc:110284 protein