PTHLH Polyclonal Antibody | Invitrogen PA5-40799 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PTHLH Polyclonal Antibody

catalog :

PA5-40799

quantity :

100 µL

price :

US 436

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 5b	van Herwijnen M, Zonneveld M, Goerdayal S, Nolte t Hoen E, Garssen J, Stahl B, et al. Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Mol Cell Proteomics. 2016;15:3412-3423 pubmed
	Ishikawa M, Ishii T, Morikawa T, Iijima Y, Sueishi K. The Effects of Fluvastatin on Indian Hedgehog Pathway in Endochondral Ossification. Cartilage. 2021;13:304S-314S pubmed publisher

product information

Product Type :

Antibody

Product Name :

PTHLH Polyclonal Antibody

Catalog # :

PA5-40799

Quantity :

100 µL

Price :

US 436

Clonality :

Polyclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 4-8 µg/mL, Western Blot: 1:1,000

Species :

Human

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone.

Immunogen :

Synthetic peptide directed towards the middle region of human PTHLH

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 4-8 µg/mL, Western Blot: 1:1,000

Aliases :

BDE2; calciotropic hormone, growth factor; HHM; osteostatin; parathyroid hormone like hormone; parathyroid hormone related peptide; parathyroid hormone-like hormone; parathyroid hormone-like hormone preproprotein; parathyroid hormone-like peptide; parathyroid hormone-like protein; parathyroid hormone-like related protein; parathyroid hormone-related peptide; parathyroid hormone-related protein; parathyroid-like peptide; PLP; PTHLH; PTH-like; PTHR; PTH-related peptide; PTH-related protein; Pthrp; PTH-rP; PTHrP[107-139]; PTHrP[1-36]; PTHrP[38-94]