SPINK1 Polyclonal Antibody | Invitrogen PA5-40796 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SPINK1 Polyclonal Antibody

catalog :

PA5-40796

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

Product Type :

Antibody

Product Name :

SPINK1 Polyclonal Antibody

Catalog # :

PA5-40796

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Western Blot: 0.2-1 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

This is a trypsin inhibitor, its physiological function is to prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT) [MIM:167800]. A disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks. Defects in SPINK1 are the cause of susceptibility to tropical calcific pancreatitis (TCP) [MIM:608189]. TCP is an idiopathic, juvenile, nonalcoholic form of chronic pancreatitis widely prevalent in several tropical countries. It can be associated with fibrocalculous pancreatic diabetes (FCPD) depending on both environmental and genetic factors. TCP differs from alcoholic pancreatitis by a much younger age of onset, pancreatic calcification, a high incidence of insulin dependent but ketosis resistant diabetes mellitus, and an exceptionally high incidence of pancreatic cancer.

Immunogen :

Synthetic peptide directed towards the N-terminal of human SPINK1 (aa 2-51).

Format :

Liquid

Applications w/Dilutions :

Western Blot: 0.2-1 ug/mL

Aliases :

calcium transport inhibitor; Caltrin; ISK1; P12; Pancreatic secretory trypsin inhibitor; pancreatic secretory trypsin inhibitor II; pancreatic secretory trypsin inhibitor type II (PSTI-II); PCTT; prostatic secretory glycoprotein; PSTI; PSTI-II; serine peptidase inhibitor Kazal type 1; serine peptidase inhibitor, Kazal type 1; serine peptidase inhibitor, Kazal type 3; serine protease inhibitor Kazal-type 1; Serine protease inhibitor Kazal-type 1-like; Serine protease inhibitor Kazal-type 3; serine protease inhibitor, Kazal type 1; serine protease inhibitor, Kazal type 3; Spink 3; Spink1; Spink1l; Spink3; TATI; TCP; Tumor-associated trypsin inhibitor