This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
HES6 Polyclonal Antibody
catalog :
PA5-40617
quantity :
100 uL
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry
product information
Product Type :
Antibody
Product Name :
HES6 Polyclonal Antibody
Catalog # :
PA5-40617
Quantity :
100 uL
Price :
US 464.00
Clonality :
Polyclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Human
Applications :
Immunohistochemistry: 5 ug/mL, Western Blot: 1.25 ug/mL
Species :
Human
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
The HES family members form a complex with TLE, the mammalian homologue of Groucho, and this interaction is mediated by the carboxy terminal WRPW motif of the HES proteins. The HES/TLE complex functions by directly binding to DNA, instead of interfering with activator proteins. Most HES family members, including HES1 and HES5, preferentially bind to the N box (CACNAG) as opposed to the E box (CANNTG). HES2 binds to both N and E box sites, while HES6 does not bind DNA. Rather, HES6 inhibits HES1 activity, thereby promoting transcription. HES1 and HES2 are expressed in a variety of adult and embryonic tissues. HES3 is expressed exclusively in cerebellar Purkinje cells, and HES5 is found solely in the nervous system. HES6 is produced in brain as well as in the limb buds of developing embryos.
Immunogen :
Synthetic peptide directed towards the C-terminal of human HES6 (aa 174-223).
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry: 5 ug/mL, Western Blot: 1.25 ug/mL
Aliases :
AI326893; bHLHb41; bHLHc23; C-HAIRY1; class B basic helix-loop-helix protein 41; Hairy and enhancer of split 6; hes family bHLH transcription factor 6; hes6; HES-6; Transcription cofactor HES-6
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA