HEY1 Polyclonal Antibody | Invitrogen PA5-40553 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HEY1 Polyclonal Antibody

catalog :

PA5-40553

quantity :

100 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 4

Reference
Kaminska A, Marek S, Pardyak L, Brzoskwinia M, Bilinska B, Hejmej A. Crosstalk between Androgen-ZIP9 Signaling and Notch Pathway in Rodent Sertoli Cells. Int J Mol Sci. 2020;21: pubmed publisher
Kaminska A, Marek S, Pardyak L, Brzoskwinia M, Pawlicki P, Bilinska B, et al. Disruption of androgen signaling during puberty affects Notch pathway in rat seminiferous epithelium. Reprod Biol Endocrinol. 2020;18:30 pubmed publisher
Kami x144 ska A, Pardyak L, Marek S, Wr xf3 bel K, Kotula Balak M, Bili x144 ska B, et al. Notch signaling regulates nuclear androgen receptor AR and membrane androgen receptor ZIP9 in mouse Sertoli cells. Andrology. 2020;8:457-472 pubmed publisher
Wimmer R, Leopoldi A, Aichinger M, Wick N, Hantusch B, Novatchkova M, et al. Human blood vessel organoids as a model of diabetic vasculopathy. Nature. 2019;565:505-510 pubmed publisher

product information

Product Type :

Antibody

Product Name :

HEY1 Polyclonal Antibody

Catalog # :

PA5-40553

Quantity :

100 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 4-8 ug/mL, Western Blot: 1-3 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Hairy/enhancer-of-split related with YRPW motif protein 1 belongs to the HEY family and is a Notch Signaling Pathway Protein. It contains one basic helix-loop-helix (bHLH) domain and one Orange domain. It is a downstream effector of Notch signaling which may be required for cardiovascular development. It acts as transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. It represses transcription by the cardiac transcriptional activators GATA4 and GATA6. Hey1 is also reported to be expressed during development of the nervous system.

Immunogen :

Synthetic peptide directed towards the C-terminal of human HEY1

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 4-8 ug/mL, Western Blot: 1-3 ug/mL

Aliases :

AI316788; AI414254; basic helix-loop-helix protein OAF1; basic helix-loop-helix transcription factor; BC8; bHLH protein Hesr-1/Hey1; bHLHb31; cardiovascular basic helix-loop-helix factor 2; cardiovascular helix-loop-helix factor 2; CHF2; CHF-2; class B basic helix-loop-helix protein 31; Hairy and enhancer of split-related protein 1; Hairy/E(spl)-related with YRPW motif 1; hairy/enhancer-of-split related with YRPW motif 1; hairy/enhancer-of-split related with YRPW motif protein 1; hairy-related transcription factor 1; Herp1; Herp2; hes related family bHLH transcription factor with YRPW motif 1; Hesr1; HESR-1; hes-related family bHLH transcription factor with YRPW motif 1; HES-related repressor protein 1; HES-related repressor protein 2; HEY1; hey1 protein; hHRT1; HRT1; HRT-1; id:ibd1292; MGC1274; mHRT1; OAF1; zgc:110572