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antibody

H3K17me2aK18ac Polyclonal Antibody

PA5-40094

50 ug

US 514.00

polyclonal

domestic rabbit

nonconjugated

human, mouse

western blot, ELISA, immunocytochemistry

H3K17me2aK18ac Polyclonal Antibody

PA5-40094

50 ug

US 514.00

Polyclonal

Antigen affinity chromatography

Rabbit

Human, Mouse

ChIP Assay: 1 ug, ChIP-Sequencing: Assay-dependent, ELISA: 1:28,800, Immunocytochemistry: 1:500, Peptide array: 1:20,000, Western Blot: 1:1,000

Human, Mouse

IgG

-20 C or -80 C if preferred

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

KLH-conjugated synthetic peptide corresponding to the region of human histone H3 containing the asymmetrically dimethylated R17 and the acetylated lysine 18 (H3R17me2(asym).

Liquid

ChIP Assay: 1 ug, ChIP-Sequencing: Assay-dependent, ELISA: 1:28,800, Immunocytochemistry: 1:500, Peptide array: 1:20,000, Western Blot: 1:1,000

Acetyl H3; Acetyl Histone H3; Di histone H3/c; dimethyl H3; di-methyl H3; Dimethyl Histone H3; di-methyl histone H3; Di-Methyl-Acetyl-H3 Arg17 Lys18; Di-Methyl-Acetyl-H3 R17 K18; Di-Methyl-Acetyl-Histone H3 Arg17 Lys18; Di-Methyl-Acetyl-Histone H3 R17 K18; H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3C; H3 K17me2aK18ac; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; H3.3A; H3.3B; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-53; H3-614; H3a; H3b; H3-B; H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3c8; H3f; H3-F; H3F1K; H3F2; H3F3; H3F3A; H3F3B; H3F3C; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3g; H3h; H3i; H3K17me2; H3K17me2a; H3K17R18me2; H3K18; H3K18ac; H3Lys17,Arg18me2; H3Lys17Arg18me2; H3R17,K18me2; Hist1; HIST1H3A; Hist1h3b; Hist1h3c; HIST1H3D; Hist1h3e; HIST1H3F; Hist1h3g; HIST1H3H; HIST1H3I; HIST1H3J; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1; Hist2h3ca2; HIST2H3D; histone 1, H3a; histone 1, H3b; histone 1, H3f; histone 1, H3h; histone 2, H3a; histone 2, H3c; histone 2, H3c2; histone 2, H3ca2; Histone 3; histone cluster 1, H3a; histone cluster 1, H3b; histone cluster 1, H3f; histone cluster 1, H3h; histone cluster 2, H3a; histone cluster 2, H3c; histone cluster 2, H3c2; histone cluster 2, H3c2, pseudogene; histone gene complex 1; histone H3; histone H3.1; Histone H3.2; histone H3.3; Histone H3.3C; histone H3.5; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; histone H3/l; Histone H3/m; histone H3/o; Histone H3K17me2; Histone H3K17me2a; Histone H3K18; Histone H3K18ac; histone variant H3.5; M32461; methyl Histone 3; methyl Histone H3; PP781