This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
RTF1 Polyclonal Antibody
catalog :
PA5-40081
quantity :
50 ug
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
fruit fly
application :
western blot, immunocytochemistry, immunoprecipitation
product information
Product Type :
Antibody
Product Name :
RTF1 Polyclonal Antibody
Catalog # :
PA5-40081
Quantity :
50 ug
Price :
US 464.00
Clonality :
Polyclonal
Purity :
Protein G
Host :
Rabbit
Reactivity :
Drosophila
Applications :
ChIP Assay: 1-5 ug, Immunocytochemistry: 1:50, Immunoprecipitation: 12 ug, Western Blot: 1:1,000
Species :
Drosophila
Isotype :
IgG
Storage :
-20 C or -80 C if preferred
Description :
Three isoforms of serine/threonine kinases, designated alphaPAK p68, betaPAK p65 and gammaPAK p62, have been shown to exhibit a high degree of sequence homology with the S. cerevisiae kinase Ste 20, involved in pheromone signaling. The alpha, beta and gammaPAK isoforms complex specifically with Rac1 and Cdc42 in their active GTP-bound state, inhibiting their intrinsic GTPase activity leading to their autophosphorylation. There are eight sites of autophosphorylation on gammaPAK, including Ser 19, Ser 141 and Thr 402, and phosphorylation of Ser 141 and Thr 402 is correlated with gammaPAK activation. Once phosphorylated and their affinity for Rac/Cdc42 reduced, the PAK isoforms disassociate from the complex to seek downstream substrates.
Immunogen :
Recombinant drosophila Rtf1 (Rtf1, Paf1/RNA polymerase II complex component, homolog) protein.
Format :
Liquid
Applications w/Dilutions :
ChIP Assay: 1-5 ug, Immunocytochemistry: 1:50, Immunoprecipitation: 12 ug, Western Blot: 1:1,000
Aliases :
2900005O08Rik; 6530416A09Rik; AI853581; AU043144; AW553985; cbp82; CG10955; CG10955-PA; CG10955-PB; Dmel CG10955; Dmel_CG10955; dRtf1; gene trap locus 7; Gtl7; KIAA0252; ortholog of mouse gene trap locus 7; RNA polymerase-associated protein Rtf1; RNA polymerase-associated protein RTF1 homolog; Rtf1; RTF1 homolog, Paf1/RNA polymerase II complex component; Rtf1 Paf1/RNA polymerase II complex component homolog; Rtf1, Paf1/RNA polymerase II complex component, homolog; Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae); Rtf1-PA; Rtf1-PB
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA