This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
FAM35A/FAM35B Polyclonal Antibody
catalog :
PA5-39363
quantity :
100 µg
price :
US 402.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot
product information
Product Type :
Antibody
Product Name :
FAM35A/FAM35B Polyclonal Antibody
Catalog # :
PA5-39363
Quantity :
100 µg
Price :
US 402.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Western Blot: 1:500-1:1,000
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20°C
Description :
Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs) (PubMed:29656893, PubMed:29789392). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection (PubMed:29656893, PubMed:29789392). Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres (PubMed:29656893). [UniProt]
Immunogen :
A synthetic peptide derived from the internal region of human FAM35A/B
Format :
Liquid
Applications w/Dilutions :
Western Blot: 1:500-1:1,000
Aliases :
3110001K24Rik; bA163M19.1; Fam35a; FAM35A1; family with sequence similarity 35 member A; family with sequence similarity 35, member A; protein FAM35A; RINN1-REV7-interacting novel NHEJ regulator 2; RINN2; Shield complex subunit 2; Shieldin complex subunit 2; SHLD2
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA