This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
AFF1 Polyclonal Antibody
catalog :
PA5-38623
quantity :
100 µg
price :
US 446
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
immunohistochemistry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
AFF1 Polyclonal Antibody
Catalog # :
PA5-38623
Quantity :
100 µg
Price :
US 446
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Immunohistochemistry (Paraffin): 1:50-1:100
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20°C
Description :
Proto-oncogene AF-4 (or FEL) is a product of a chromosomal aberration of the human gene AFF1, which is associated with acute leukemias. The fusion of AF-4 on chromosome band 4q21 with the mixed lineage leukemia (MLL or HRX) gene on 11q23 results in a MLL-AF-4 chimeric transcription factor in which AF-4 contributes transcriptional effector properties and requires cell-specific accessory factors. MLL is involved in several chromosomal translocations associated with acute myeloid and lymphoid leukemia. The MLL-AF-4 fusion protein is expressed in all normal hematopoietic cells.
Immunogen :
A synthetic peptide derived from the N-terminal region of human AF4
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:50-1:100
Aliases :
9630032B01Rik; Af4; AF4/FMR2 family member 1; AF4/FMR2 family, member 1; Aff1; ALL1-fused gene from chromosome 4 protein; AW319193; FEL; homolog of human MLLT2 unidentified; MLLT2; Mllt2h; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 2; myeloid/lymphoid or mixed-lineage leukemia translocated to 2 homolog; PBM1; pre-B-cell monocytic leukemia partner 1; protein AF-4; Protein FEL; Proto-oncogene AF4; Rob; robotic; translocated to, 2
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA