This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Phospho-RBL1 (Thr369) Polyclonal Antibody
catalog :
PA5-38423
quantity :
100 µg
price :
US 436
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
immunohistochemistry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
Phospho-RBL1 (Thr369) Polyclonal Antibody
Catalog # :
PA5-38423
Quantity :
100 µg
Price :
US 436
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Immunohistochemistry (Paraffin): 1:50-1:100, peptide-ELISA: 1:5000
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20°C
Description :
RB-like 1 is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and RB-like 1 can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that RB-like 1 may also be a tumor suppressor.
Immunogen :
A synthetic phosphopeptide derived from human RBL1 around the phosphorylation site of Thr369 (P-S-TP-P-L)
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:50-1:100, peptide-ELISA: 1:5000
Aliases :
107 kDa retinoblastoma-associated protein; AW547426; CP107; MGC40006; p107; pRb1; RB transcriptional corepressor like 1; RBL1; retinoblastoma-like 1; retinoblastoma-like 1 (p107); Retinoblastoma-like protein 1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA