CaMKII alpha/beta/delta Polyclonal Antibody | Invitrogen PA5-38239 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CaMKII alpha/beta/delta Polyclonal Antibody

catalog :

PA5-38239

quantity :

100 µg

price :

US 394.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

immunohistochemistry, immunohistochemistry - paraffin section

citations: 5

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:200; loading ...; fig 1	Bitzenhofer S, Ahlbeck J, Wolff A, Wiegert J, Gee C, Oertner T, et al. Layer-specific optogenetic activation of pyramidal neurons causes beta-gamma entrainment of neonatal networks. Nat Commun. 2017;8:14563 pubmed publisher
	Bitzenhofer S, Pöpplau J, Chini M, Marquardt A, Hanganu Opatz I. A transient developmental increase in prefrontal activity alters network maturation and causes cognitive dysfunction in adult mice. Neuron. 2021;109:1350-1364.e6 pubmed publisher
	Chini M, Pöpplau J, Lindemann C, Carol Perdiguer L, Hnida M, Oberländer V, et al. Resolving and Rescuing Developmental Miswiring in a Mouse Model of Cognitive Impairment. Neuron. 2020;105:60-74.e7 pubmed publisher
	Xu X, Chini M, Bitzenhofer S, Hanganu Opatz I. Transient Knock-Down of Prefrontal DISC1 in Immune-Challenged Mice Causes Abnormal Long-Range Coupling and Cognitive Dysfunction throughout Development. J Neurosci. 2019;39:1222-1235 pubmed publisher
	Bitzenhofer S, Ahlbeck J, Hanganu Opatz I. Methodological Approach for Optogenetic Manipulation of Neonatal Neuronal Networks. Front Cell Neurosci. 2017;11:239 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CaMKII alpha/beta/delta Polyclonal Antibody

Catalog # :

PA5-38239

Quantity :

100 µg

Price :

US 394.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 1:50-1:100

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20°C

Description :

The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+ and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes, designated alpha, beta, gamma and delta, which may or may not be co-expressed in the same tissue type. CaMKII alpha is autophosphorylated on Thr 286 upon the binding of the Ca2+/CaM complex to the autoinhibitory domain of CaMKII. This process is called Ca2+/CaM trapping, which is thought to be involved in the synaptic encoding of information.

Immunogen :

A synthetic peptide derived from the internal region of human CaMK2 alpha/beta/sigma

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:50-1:100

Aliases :

[d]-CaMKII; 2810011D23Rik; 8030469K03Rik; alpha CaM kinase II; alpha-CaMKII; Ca++/calmodulin-dependent protein kinase 2 delta subunit; Ca++/calmodulin-dependent protein kinase II beta subunit; Ca++/calmodulin-dependent protein kinase II delta subunit; Ca++/calmodulin-dependent protein kinase II, delta subunit; Ca2+/calmodulin-dependent protein kinase II alpha; Calci; calcium/calmodulin dependent protein kinase II alpha; calcium/calmodulin dependent protein kinase II beta; calcium/calmodulin dependent protein kinase II delta; calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta; calcium/calmodulin-dependent protein kinase (CaM kinase) II delta; calcium/calmodulin-dependent protein kinase II alpha; calcium/calmodulin-dependent protein kinase II alpha subunit; calcium/calmodulin-dependent protein kinase II alpha-B subunit; calcium/calmodulin-dependent protein kinase II beta; calcium/calmodulin-dependent protein kinase II delta; calcium/calmodulin-dependent protein kinase II, beta; calcium/calmodulin-dependent protein kinase II, delta; calcium/calmodulin-dependent protein kinase type II alpha chain; calcium/calmodulin-dependent protein kinase type II beta chain; calcium/calmodulin-dependent protein kinase type II delta chain; calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase type II subunit beta; calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II alpha subunit; CaM kinase II beta subunit; CaM kinase II delta subunit; caM kinase II subunit alpha; CaM kinase II subunit beta; caM kinase II subunit delta; CAM2; CAMK; CaMK II; CAMK1; Camk2; CaMK2 delta; CaMK-2 delta; CaMK2- delta; Camk2a; CaMK-2a; CaMK2-a; Camk2b; Camk2d; CAMK2G; CAMKA; CAMKB; CAMKD; CAMKG; Camki; CaMKII; CAMK-II; CaMK-II alpha subunit; CaMK-II delta subunit; caMK-II subunit alpha; caMK-II subunit beta; caMK-II subunit delta; CaMKIINalpha; caM-kinase II alpha chain; CaM-kinase II beta chain; CaM-kinase II delta chain; Ck2b; KIAA0968; Kiaa4163; mKIAA0968; PK2CDD; PKCCD; proline rich calmodulin-dependent protein kinase; R74975; RATCAMKI