product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
betatrophin Polyclonal Antibody
catalog :
PA5-38043
quantity :
100 ug
price :
US 470.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 4
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 5
Arefanian H, Al Khairi I, Khalaf N, Cherian P, Kavalakatt S, Madhu D, et al. Increased expression level of ANGPTL8 in white adipose tissue under acute and chronic cold treatment. Lipids Health Dis. 2021;20:117 pubmed publisher
Li D, Huang L, Kan R, Meng X, Wang S, Zou H, et al. LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis. Nat Commun. 2023;14:4436 pubmed publisher
Demircan S, Onalan E, Kulo x11f lu T, Ayd x131 n S, Yal xe7 x131 n M, G xf6 zel N, et al. Effects of vitamin D on apoptosis and betatrophin in the kidney tissue of experimental diabetic rats. Acta Biomed. 2020;91:e2020089 pubmed publisher
Chen S, Feng M, Zhang S, Dong Z, Wang Y, Zhang W, et al. Angptl8 mediates food-driven resetting of hepatic circadian clock in mice. Nat Commun. 2019;10:3518 pubmed publisher
product information
Product Type :
Antibody
Product Name :
betatrophin Polyclonal Antibody
Catalog # :
PA5-38043
Quantity :
100 ug
Price :
US 470.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 1-2 ug/mL
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
Maintain refrigerated at 2-8 C for up to 3 months. For long term storage store at -20 C
Description :
The Betatrophin protein, also known as the hepatocellular carcinoma-associated protein TD26, is an adipocyte- and liver-enriched insulin targeted gene that is thought to play a role in lipid metabolism be regulating serum triglyceride levels. Betatrophin is closely related to the angiopoietin-like (ANGPTL) protein family. Betatrophin mRNA increases in the cold environment and after treatment with a high-fat diet, while its mRNA levels decrease in response to fasting, suggesting that it may play a role in mediating thermogenesis and energy homeostasis.
Immunogen :
16 amino acid peptide near the amino terminus of human Betatrophin
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 1-2 ug/mL
Aliases :
angiopoietin like 8; angiopoietin-like 8; angiopoietin-like protein 8; Angptl8; betatrophin; betatrophin variant 1; betatrophin variant 2; C19orf80; EG624219; Gm6484; hepatocellular carcinoma-associated gene TD26; hepatocellular carcinoma-associated protein TD26; hepatocellular carcinoma-associated protein TD26 homolog; lipasin; LOC100361444; predicted gene 6484; PRO1185; PVPA599; rCG31799-like; refeeding-induced fat and liver protein; Rifl; TD26; UNQ599/PRO1185
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA