MFN1 Polyclonal Antibody | Invitrogen PA5-38042 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MFN1 Polyclonal Antibody

catalog :

PA5-38042

quantity :

100 ug

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

citations: 3

Reference
Mallard J, Hucteau E, Charles A, Bender L, Baeza C, P xe9 lissie M, et al. Chemotherapy impairs skeletal muscle mitochondrial homeostasis in early breast cancer patients. J Cachexia Sarcopenia Muscle. 2022;13:1896-1907 pubmed publisher
Park M, Hwang I, Kwak T, Lim J, Hwang S, Cho S. Low expression of mitofusin 1 is associated with mitochondrial dysfunction and apoptosis in porcine somatic cell nuclear transfer embryos. Anim Sci J. 2020;91:e13430 pubmed publisher
Torres M, McLaughlin K, Renegar R, Valsaraj S, Whitehurst K, Sharaf O, et al. Intracardiac administration of ephrinA1-Fc preserves mitochondrial bioenergetics during acute ischemia/reperfusion injury. Life Sci. 2019;239:117053 pubmed publisher

product information

Product Type :

Antibody

Product Name :

MFN1 Polyclonal Antibody

Catalog # :

PA5-38042

Quantity :

100 ug

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 5 ug/mL, Western Blot: 1-2 ug/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Maintain refrigerated at 2-8 C for up to 3 months. For long term storage store at -20 C

Description :

Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane.

Immunogen :

17 amino acid peptide near the amino terminus of human MFN1

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 5 ug/mL, Western Blot: 1-2 ug/mL

Aliases :

2310002F04Rik; 6330416C07Rik; D3Ertd265e; DKFZp762F247; EC 3.6.5; FLJ20693; Fzo homolog; Fzo1b; hfzo1; hfzo2; HR2; Mfn1; MFN2; MGC41806; mitochondrial mitofusin 1; mitochondrial transmembrane GTPase Fzo-1; mitochondrial transmembrane GTPase FZO1B; mitochondrial transmembrane GTPase FZO-2; mitofusin 1; mitofusin 2; mitofusin-1; mKIAA4032; putative transmembrane GTPase; transmembrane GTPase MFN1