product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
SLC29A3 Polyclonal Antibody
catalog :
PA5-38039
quantity :
100 ug
price :
US 454.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 3
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig s5c
  • western blot; human; 1:1000; loading ...; fig s5c
Persaud A, Nair S, Rahman M, Raj R, Weadick B, Nayak D, et al. Facilitative lysosomal transport of bile acids alleviates ER stress in mouse hematopoietic precursors. Nat Commun. 2021;12:1248 pubmed publisher
Nair S, Strohecker A, Persaud A, Bissa B, Muruganandan S, McElroy C, et al. Adult stem cell deficits drive Slc29a3 disorders in mice. Nat Commun. 2019;10:2943 pubmed publisher
Riachi M, Bas F, Darendeliler F, Hussain K. A novel 3' untranslated region mutation in the SLC29A3 gene associated with pigmentary hypertrichosis and non-autoimmune insulin-dependent diabetes mellitus syndrome. Pediatr Diabetes. 2019;20:474-481 pubmed publisher
product information
Product Type :
Antibody
Product Name :
SLC29A3 Polyclonal Antibody
Catalog # :
PA5-38039
Quantity :
100 ug
Price :
US 454.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 1-2 ug/mL
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
Maintain refrigerated at 2-8 C for up to 3 months. For long term storage store at -20 C
Description :
SLC29A3 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis. SLC29A3 is a transmembrane glycoprotein that localizes to the lysosomal membrane and is a broad selectivity, low affinity nucleoside transporter. Mutations in the SLC29A3 gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism. A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus.
Immunogen :
19 amino acid peptide near the amino terminus of human SLC29A3
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 1-2 ug/mL
Aliases :
4933435C21Rik; AW987637; Ent3; Equilibrative nucleoside transporter 3; HCLAP; hENT3; HJCD; mENT3; PHID; Slc29a3; solute carrier family 29 (equilibrative nucleoside transporter), member 3; solute carrier family 29 (nucleoside transporters), member 3; solute carrier family 29 member 3; UNQ717/PRO1380
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA