This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Phospho-CaMKII beta/gamma/delta (Thr287) Polyclonal Antibody
catalog :
PA5-37833
quantity :
100 uL
price :
US 514.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot
citations: 12
Reference
Shiba N, Yang X, Sato M, Kadota S, Suzuki Y, Agata M, et al. Efficacy of exon-skipping therapy for DMD cardiomyopathy with mutations in actin binding domain 1. Mol Ther Nucleic Acids. 2023;34:102060 pubmed publisher
Han J, Jung H. Synergistic Anticancer Effect of a Combination of Berbamine and Arcyriaflavin A against Glioblastoma Stem-like Cells. Molecules. 2022;27: pubmed publisher
Wu J, Liu T, Shi S, Fan Z, Hiram R, Xiong F, et al. Dapagliflozin reduces the vulnerability of rats with pulmonary arterial hypertension-induced right heart failure to ventricular arrhythmia by restoring calcium handling. Cardiovasc Diabetol. 2022;21:197 pubmed publisher
Wang X, Bian Y, Wong C, Lu J, Lee S. TRPV1 Modulator Ameliorates Alzheimer-Like Amyloid-β Neuropathology via Akt/Gsk3β-Mediated Nrf2 Activation in the Neuro-2a/APP Cell Model. Oxid Med Cell Longev. 2022;2022:1544244 pubmed publisher
Guo Y, Yu Z, Wu J, Gong H, Kesteven S, Iismaa S, et al. The Ca2+-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy. elife. 2021;10: pubmed publisher
Baine S, Bonilla I, Belevych A, Stepanov A, Dorn L, Terentyeva R, et al. Pyridostigmine improves cardiac function and rhythmicity through RyR2 stabilization and inhibition of STIM1-mediated calcium entry in heart failure. J Cell Mol Med. 2021;25:4637-4648 pubmed publisher
Dietze R, Hammoud M, Gomez Serrano M, Unger A, Bieringer T, Finkernagel F, et al. Phosphoproteomics identify arachidonic-acid-regulated signal transduction pathways modulating macrophage functions with implications for ovarian cancer. Theranostics. 2021;11:1377-1395 pubmed publisher
Hekman R, Hume A, Goel R, Abo K, Huang J, Blum B, et al. Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2. Mol Cell. 2020;80:1104-1122.e9 pubmed publisher
Chowdhury S, Warren C, Simon J, Ryba D, Batra A, Varga P, et al. Modifications of Sarcoplasmic Reticulum Function Prevent Progression of Sarcomere-Linked Hypertrophic Cardiomyopathy Despite a Persistent Increase in Myofilament Calcium Response. Front Physiol. 2020;11:107 pubmed publisher
Shrestha A, Sultana R, Lee C, Ogundele O. SK Channel Modulates Synaptic Plasticity by Tuning CaMKIIα/β Dynamics. Front Synaptic Neurosci. 2019;11:18 pubmed publisher
Nie J, Ta N, Liu L, Shi G, Kang T, Zheng Z. Activation of CaMKII via ER-stress mediates coxsackievirus B3-induced cardiomyocyte apoptosis. Cell Biol Int. 2019;: pubmed publisher
Zhong P, Quan D, Huang Y, Huang H. CaMKII Activation Promotes Cardiac Electrical Remodeling and Increases the Susceptibility to Arrhythmia Induction in High-fat Diet-Fed Mice With Hyperlipidemia Conditions. J Cardiovasc Pharmacol. 2017;70:245-254 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Phospho-CaMKII beta/gamma/delta (Thr287) Polyclonal Antibody
Catalog # :
PA5-37833
Quantity :
100 uL
Price :
US 514.00
Clonality :
Polyclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Western Blot: 1:500-1:1,000
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
-20 C
Description :
The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+ and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes, designated alpha, beta, gamma and delta, which may or may not be coexpressed in the same tissue type. CaMKIV is stimulated by Ca2+ and CaM but also requires phosphorylation by a CaMK for full activation.
Immunogen :
Peptide sequence around phosphorylation site of Threonine 287 (Q-E-T(p)-V-E) derived from Human CaMK2- beta/ gamma/ delta
Format :
Liquid
Applications w/Dilutions :
Western Blot: 1:500-1:1,000
Aliases :
[d]-CaMKII; 2810011D23Rik; 8030469K03Rik; Ca++/calmodulin-dependent protein kinase 2 delta subunit; Ca++/calmodulin-dependent protein kinase II beta subunit; Ca++/calmodulin-dependent protein kinase II delta subunit; Ca++/calmodulin-dependent protein kinase II, delta subunit; Ca2+/calmodulin-dependent protein kinase II; calcium/calmodulin dependent protein kinase II beta; calcium/calmodulin dependent protein kinase II delta; calcium/calmodulin dependent protein kinase II gamma; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta; calcium/calmodulin-dependent protein kinase (CaM kinase) II delta; calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma; calcium/calmodulin-dependent protein kinase II beta; calcium/calmodulin-dependent protein kinase II delta; calcium/calmodulin-dependent protein kinase II gamma; calcium/calmodulin-dependent protein kinase II, beta; calcium/calmodulin-dependent protein kinase II, delta; calcium/calmodulin-dependent protein kinase type II beta chain; calcium/calmodulin-dependent protein kinase type II delta chain; calcium/calmodulin-dependent protein kinase type II gamma chain; calcium/calmodulin-dependent protein kinase type II subunit beta; Calcium/calmodulin-dependent protein kinase type II subunit delta; calcium/calmodulin-dependent protein kinase type II subunit gamma; CaM kinase II beta subunit; CaM kinase II delta subunit; caM kinase II subunit beta; CaM kinase II subunit delta; caM kinase II subunit gamma; CAM2; CAMK; CaMK II; CAMK1; CAMK2; Camk2b; Camk2d; CAMK2G; CAMKB; CAMKD; CAMKG; Camki; CAMK-II; CaMK-II delta subunit; caMK-II subunit beta; caMK-II subunit delta; caMK-II subunit gamma; caM-kinase II beta chain; caM-kinase II delta chain; caM-kinase II gamma chain; Ck2b; Kiaa4163; proline rich calmodulin-dependent protein kinase; RATCAMKI
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA