TAP2 Polyclonal Antibody | Invitrogen PA5-37414 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TAP2 Polyclonal Antibody

catalog :

PA5-37414

quantity :

100 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 3

Reference
Cheng Z, Wang H, Yang Z, Li J, Chen X. LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer. BMC Cancer. 2023;23:1128 pubmed publisher
Tailor A, Estephan H, Parker R, Woodhouse I, Abdulghani M, Nicastri A, et al. Ionizing Radiation Drives Key Regulators of Antigen Presentation and a Global Expansion of the Immunopeptidome. Mol Cell Proteomics. 2022;21:100410 pubmed publisher
Shen M, Smith H, Wei Y, Jiang Y, Zhao S, Wang N, et al. Pharmacological disruption of the MTDH-SND1 complex enhances tumor antigen presentation and synergizes with anti-PD-1 therapy in metastatic breast cancer. Nat Cancer. 2022;3:60-74 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TAP2 Polyclonal Antibody

Catalog # :

PA5-37414

Quantity :

100 uL

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules.

Immunogen :

Recombinant full length human TAP2

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2,000

Aliases :

ABC transporter, MHC 2; ABC18; ABCB3; AI462429; Antigen peptide transporter 2; APT2; ATP dependent transport protein family member; ATP-binding cassette sub-family B member 3; ATP-binding cassette, sub-family B (MDR/TAP), member 3; Cim; D6S217E; Ham2; Ham-2; Histocompatibility antigen modifier 2; jas; MTP2; Peptide supply factor 2; peptide transporter involved in antigen processing 2; Peptide transporter PSF2; Peptide transporter TAP2; PSF2; PSF-2; Really interesting new gene 11 protein; RING11; TAP2; Tap-2; Transporter 2 ABC (ATP binding cassette); transporter 2 ATP-binding cassette sub-family B; transporter 2, ABC (ATP binding cassette); transporter 2, ATP binding cassette subfamily B member; transporter 2, ATP-binding cassette, sub-family B (MDR/TAP); Y1