USP35 Polyclonal Antibody | Invitrogen PA5-37232 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

USP35 Polyclonal Antibody

catalog :

PA5-37232

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

citations: 1

Reference
Lv T, Zhang B, Jiang C, Zeng Q, Yang J, Zhou Y. USP35 promotes hepatocellular carcinoma progression by protecting PKM2 from ubiquitination‑mediated degradation. Int J Oncol. 2023;63: pubmed publisher

product information

Product Type :

Antibody

Product Name :

USP35 Polyclonal Antibody

Catalog # :

PA5-37232

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Western Blot: 1:500-1:1,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

p73 protein is a member of the p53 family of proteins. The tumor-suppressor protein p53 exhibits sequence specific DNA-binding, directly interacts with various cellular and viral proteins, and induces cell cycle arrest in response to DNA damage. In response to signals generated by a variety of genotoxic stresses, e.g, UV irradiation or DNA damage, p53 is expressed and undergoes post-translational modification that results in its accumulation in the nucleus. Activation of p53 leads to cell cycle arrest and in some cases to apoptosis, resulting in the inability of genetically damaged cells to proliferate. Thus, the p53-dependent pathways help to maintain genomic stability by eliminating damaged cells. The accumulation of high levels of p53 is a potential marker for malignancy.

Immunogen :

A synthetic peptide corresponding to residues in human USP35

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:500-1:1,000

Aliases :

Deubiquitinating enzyme 35; Gm1088; Gm493; KIAA1372; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 35; RGD1565984; Ubiquitin carboxyl-terminal hydrolase 35; ubiquitin specific peptidase 35; ubiquitin specific protease 35; ubiquitin thioesterase 35; ubiquitin thiolesterase 35; ubiquitin-specific-processing protease 35; USP34; USP35