This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
POM121 Polyclonal Antibody
catalog :
PA5-36498
quantity :
100 uL
price :
US 454.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
citations: 1
Reference
Eftekharzadeh B, Daigle J, Kapinos L, Coyne A, Schiantarelli J, Carlomagno Y, et al. Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease. Neuron. 2018;99:925-940.e7 pubmed publisher
product information
Product Type :
Antibody
Product Name :
POM121 Polyclonal Antibody
Catalog # :
PA5-36498
Quantity :
100 uL
Price :
US 454.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:1,000
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
POM121 (POM121 membrane glycoprotein), also known as POM121A (nuclear envelope pore membrane protein POM 121A), NUP121 (nucleoporin Nup121) or pore membrane protein of 121 kDa, is a 1,249 amino acid single-pass membrane protein that exists as three alternatively spiced isoforms and belongs to the POM121 family. Encoded by a gene that maps to human chromosome 7q11.23, POM121 is highly conserved and localizes to nucleus membrane and endoplasmic reticulum membrane. An essential component of the nuclear pore complex (NPC), POM121 is mandatory for nuclear envelope formation and may play a role in biogenesis of the NPC. POM121 associates with the central spoke ring complex and is involved in anchoring components of the pore complex to the pore membrane by way of its F-X-F-G repeat-containing domain. POM121 overexpression induces the formation of cytoplasmic annulate lamellae (AL).
Immunogen :
Synthetic peptide corresponding to the C-terminual of human POM121
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:1,000
Aliases :
2610027A18Rik; C80273; KIAA0618; mKIAA0618; Nuclear envelope pore membrane protein POM 121; nuclear envelope pore membrane protein POM 121A; nuclear envelope pore membrane protein POM 121C; nuclear pore membrane glycoprotein 121 kD; nuclear pore membrane protein 121; nuclear pore membrane protein 121 kDa; nuclear pore membrane protein 121-2; nucleoporin Nup121; Nup121; p145; Pom121; POM121 membrane glycoprotein; POM121 membrane glycoprotein C; POM121 transmembrane nucleoporin; POM121 transmembrane nucleoporin C; POM121-2; POM121A; POM121B; POM121C; Pore membrane protein of 121 kDa; pore membrane protein of 121 kDa C
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA