AMPK gamma-1,2,3 Polyclonal Antibody | Invitrogen PA5-36314 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

AMPK gamma-1,2,3 Polyclonal Antibody

catalog :

PA5-36314

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Zimmermann H, Yang W, Kasica N, Zhou X, Wang X, Beckelman B, et al. Brain-specific repression of AMPKα1 alleviates pathophysiology in Alzheimer's model mice. J Clin Invest. 2020;130:3511-3527 pubmed publisher

product information

Product Type :

Antibody

Product Name :

AMPK gamma-1,2,3 Polyclonal Antibody

Catalog # :

PA5-36314

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:200

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The 5-AMP activated protein kinase (AMPK), a member of the SNF1 (sucrose non fermentor) kinase family, is a heterotrimeric protein comprise of alpha (63 kDa), beta (30 kDa) and gamma (38 kDa) subunits. The alpha subunit is the catalytic subunit, while beta and gamma are non catalytic subunits (although they have been found to interact with the active subunit in liver). AMPK regulates fatty acid and sterol synthesis by phosphorylation of acetyl-CoA as well as cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase. AMPK is activated by AMP and can be also regulated by treatment with purified protein phosphatase in vitro.

Immunogen :

Synthetic peptide corresponding to amino acids 50-100 of human AMPK gamma1

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:200

Aliases :

2410051C13Rik; 5'-AMP-activated protein kinase subunit gamma-1; 5'-AMP-activated protein kinase subunit gamma-2; 5'-AMP-activated protein kinase subunit gamma-3; 5'-AMP-activated protein kinase, gamma-1 subunit; 5-AMP-activated protein kinase, gamma-2 subunit; 5'-AMP-activated protein kinase, gamma-3 subunit; AA571379; AAKG; AAKG2; adenosine monophosphate-activated protein kinase gamma 2-subunit; AI854673; Amkg3; AMP-activated protein kinase gamma 3 subunit; AMP-activated protein kinase gamma subunit; AMP-activated protein kinase gamma2 subunit; AMP-activated protein kinase, noncatalytic gamma-1 subunit; ampk gamma; AMPK gamma 2; AMPK gamma1; AMPK- gamma1; AMPK gamma-1 chain; AMPK gamma2; AMPK- gamma2; AMPK gamma-2 chain; AMPK gamma3; AMPK- gamma3; AMPK gamma-3 chain; AMPK subunit gamma-1; AMPK subunit gamma-2; AMPK subunit gamma-3; AMPKg; Ampkg3; AMPKg3L; AMPKg3S; BB036179; CMH6; H91620p; Prkaac; Prkag1; PRKAG2; PRKAG3; Prkga1; Protein kinase AMP-activated gamma; protein kinase AMP-activated non-catalytic subunit gamma 1; protein kinase AMP-activated non-catalytic subunit gamma 2; protein kinase AMP-activated non-catalytic subunit gamma 3; protein kinase, AMP-activated, gamma 1 non-catalytic subunit; protein kinase, AMP-activated, gamma 2 non-catalytic subunit; protein kinase, AMP-activated, gamma 3 non-catalytic subunit; protein kinase, AMP-activated, gamma 3 non-catatlytic subunit; WPWS