CUG-BP Polyclonal Antibody | Invitrogen PA5-36277 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CUG-BP Polyclonal Antibody

catalog :

PA5-36277

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

CUG-BP Polyclonal Antibody

Catalog # :

PA5-36277

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

CUG-BP1 and CUG-BP2 are proteins that bind specifically to (CUG)8 oligonucleotides in vitro. While CUG-BP1 has the major binding activity in normal cells, nuclear CUG-BP2 binding activity increases in DM cells. Both CUG-BP1 and CUG-BP2 are isoforms of a novel heterogeneous nuclear ribonucleoprotein (hnRNP), hNab50. CUG-BP1, an RNA CUG triplet repeat binding protein, regulates splicing and translation of various RNAs. Expansion of RNA CUG repeats in the DMPK in DM is associated with alterations in binding activity of CUG-BP1 as well as alterations in the translation of the C/EBPb transcription factor. CUG-BP1 is an important regulator of initiation from different AUG codons of C/EBPb mRNA.

Immunogen :

Synthetic peptide corresponding to amino acids 62-115 of human CUG-BP1/2

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500

Aliases :

1600010O03Rik; 50 kDa nuclear polyadenylated RNA-binding protein; AA407467; B230218O03; B230345P09Rik; Brain protein F41; Brunol2; BRUNOL3; bruno-like 2; bruno-like protein 2; Bruno-like protein 3; C88023; Celf1; CELF-1; Celf2; CELF-2; CUG RNA-binding protein; CUG triplet repeat RNA-binding protein 1; CUG triplet repeat RNA-binding protein 2; CUG triplet repeat, RNA binding protein 1; CUG triplet repeat, RNA binding protein 2; CUG triplet repeat, RNA-binding protein 1; CUGBP; CUG-BP; CUG-BP- and ETR-3-like factor 1; CUG-BP- and ETR-3-like factor 2; Cugbp- and Etr3-like factor 2; CUGBP Elav-like family member 1; CUGBP Elav-like family member 2; CUGBP, Elav-like family member 1; CUGBP, Elav-like family member 2; Cugbp1; CUG-BP1; Cugbp2; CUG-BP2; D230046B21Rik; D2Wsu101e; deadenylation factor CUG-BP; Deadenylation factor EDEN-BP; EDEN-BP; EDEN-BP homolog; ELAV-type RNA-binding protein 3; embryo deadenylation element binding protein; embryo deadenylation element-binding protein homolog; ETR3; ETR-3; hNab50; hNAPOR; mETR-3; mNapor; NAB50; Napor; Napor-2; Neuroblastoma apoptosis-related RNA-binding protein; nuclear polyadenylated RNA-binding protein, 50-kD; RNA-binding protein BRUNOL-2; RNA-binding protein Brunol3; RNA-binding protein BRUNOL-3; rNapor