PMS1 Polyclonal Antibody | Invitrogen PA5-35952 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PMS1 Polyclonal Antibody

catalog :

PA5-35952

quantity :

100 µL

price :

US 436.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:2500; loading ...; fig 4a	Abildgaard A, Stein A, Nielsen S, Schultz Knudsen K, Papaleo E, Shrikhande A, et al. Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome. elife. 2019;8: pubmed publisher

product information

Product Type :

Antibody

Product Name :

PMS1 Polyclonal Antibody

Catalog # :

PA5-35952

Quantity :

100 µL

Price :

US 436.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunoprecipitation: 1:100-1:500, Western Blot: 1:500-1:3,000

Species :

Human

Isotype :

IgG

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.

Immunogen :

Recombinant fragment corresponding to a region within amino acids 288 and 545 of PMS1

Format :

Liquid

Applications w/Dilutions :

Immunoprecipitation: 1:100-1:500, Western Blot: 1:500-1:3,000

Aliases :

DNA mismatch repair protein PMS1; HNPCC3; hPMS1; human homolog of yeast mutL; mismatch repair gene PMSL1; MLH2; PMS1; PMS1 homolog 1, mismatch repair system component; PMS1 postmeiotic segregation increased 1; PMS1 protein homolog 1; PMSL1; postmeiotic segregation increased 1 (S. cerevisiae); rhabdomyosarcoma antigen MU-RMS-40.10B; rhabdomyosarcoma antigen MU-RMS-40.10E

more info or order :

Invitrogen product webpage