Procollagen I C-Peptide Polyclonal Antibody | Invitrogen PA5-35380 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Procollagen I C-Peptide Polyclonal Antibody

catalog :

PA5-35380

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, domestic sheep

application :

western blot, immunohistochemistry

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1b	Butoi E, Gan A, Tucureanu M, Stan D, Macarie R, Constantinescu C, et al. Cross-talk between macrophages and smooth muscle cells impairs collagen and metalloprotease synthesis and promotes angiogenesis. Biochim Biophys Acta. 2016;1863:1568-78 pubmed publisher
	Diaz Espinosa A, Link P, Sicard D, Jorba I, Tschumperlin D, Haak A. Dopamine D1 receptor stimulates cathepsin K-dependent degradation and resorption of collagen I in lung fibroblasts. J Cell Sci. 2020;133: pubmed publisher

product information

Product Type :

Antibody

Product Name :

Procollagen I C-Peptide Polyclonal Antibody

Catalog # :

PA5-35380

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Ovine, Rat

Applications :

Immunohistochemistry: 1:100, Western Blot: 1:1,000

Species :

Human, Mouse, Ovine, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Collagen type I is present in soft connective tissue and bone where it represents approximately 90% of the organix matrix. Collagen type I is produced from procollagen when two teloterminal propeptides are digested from the procursor and released into the circulation. The propeptide levels can be measured in serum as indicators of collagen production. Elevated values of these propeptides in serum are found in patients with various bone metabolism defects. Procollagen type I C-terminal propeptide (PICP) has a molecular weight of approximately 100 kDa and the normal range in serum depends on age and sex.

Immunogen :

Synthetic peptide corresponding to amino acid residues specific to the C-terminal region of human collagen 1, alpha 1 telopeptide conjugated to KLH

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: 1:100, Western Blot: 1:1,000

Aliases :

Alpha-1 type I collagen; alpha1(I) procollagen; COL1A1; collagen alpha 1 chain type I; collagen alpha-1(I) chain; collagen alpha-1(I) chain preproprotein; collagen of skin, tendon and bone, alpha-1 chain; collagen type I alpha 1; collagen, type I, alpha 1; C-terminal Collagen; EDSC; OI1; OI2; OI3; OI4; PICP; pro-alpha-1 collagen type 1; Procol; Procollagen; type I proalpha 1; type I procollagen alpha 1 chain

more info or order :

Invitrogen product webpage