Procollagen I N-Peptide Polyclonal Antibody | Invitrogen PA5-35379 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Procollagen I N-Peptide Polyclonal Antibody

catalog :

PA5-35379

quantity :

100 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

citations: 1

Reference
Di Campli M, Azouz A, Assabban A, Scaillet J, Splittgerber M, Van Keymeulen A, et al. The mononuclear phagocyte system contributes to fibrosis in post-transplant obliterans bronchiolitis. Eur Respir J. 2021;57: pubmed publisher

product information

Product Type :

Antibody

Product Name :

Procollagen I N-Peptide Polyclonal Antibody

Catalog # :

PA5-35379

Quantity :

100 uL

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry: 1:100, Western Blot: 1:1,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Procollagen type I N-terminal propeptide (P1NP) is a specific marker of bone formation, reflecting the synthesis of type I collagen, which constitutes the major part of the bone matrix. P1NP is derived during the conversion of procollagen to collagen, produced by osteoblasts during bone formation. Its primary clinical application lies in the diagnosis and monitoring of metabolic bone diseases, particularly osteoporosis. In osteoporotic patients, P1NP levels can predict bone mineral density (BMD) responses to treatments like teriparatide and romosozumab. Low serum levels of P1NP are indicative of a high risk of BMD loss, providing a valuable tool for premenopausal women with systemic lupus erythematosus (SLE) and other conditions affecting bone health.

Immunogen :

Synthetic peptide corresponding to amino acid residues specific to human collagen 1, alpha 1 propeptide conjugated to KLH

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: 1:100, Western Blot: 1:1,000

Aliases :

P1NP; Procollagen I N