This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
NMDAR2A Polyclonal Antibody
catalog :
PA5-35377
quantity :
100 uL
price :
US 470.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, domestic rabbit
application :
western blot, immunohistochemistry, immunoprecipitation
citations: 5
Reference
Ru Q, Lu Y, Saifullah A, Blanco F, Yao C, Cata J, et al. TIAM1-mediated synaptic plasticity underlies comorbid depression-like and ketamine antidepressant-like actions in chronic pain. J Clin Invest. 2022;132: pubmed publisher
Catania M, Colombo L, Sorrentino S, Cagnotto A, Lucchetti J, Barbagallo M, et al. A novel bio-inspired strategy to prevent amyloidogenesis and synaptic damage in Alzheimer's disease. Mol Psychiatry. 2022;27:5227-5234 pubmed publisher
Angelini C, Morellato A, Alfieri A, Pavinato L, Cravero T, Bianciotto O, et al. p140Cap regulates the composition and localization of the NMDAR complex in synaptic lipid rafts. J Neurosci. 2022;42:7183-200 pubmed publisher
Guo Y, Zhang W, Chen X, Fu J, Cheng W, Song D, et al. Timing-dependent LTP and LTD in mouse primary visual cortex following different visual deprivation models. PLoS ONE. 2017;12:e0176603 pubmed publisher
Ma Q, Yang J, Milner T, Vonsattel J, Palko M, Tessarollo L, et al. SorCS2-mediated NR2A trafficking regulates motor deficits in Huntington's disease. JCI Insight. 2017;2: pubmed publisher
product information
Product Type :
Antibody
Product Name :
NMDAR2A Polyclonal Antibody
Catalog # :
PA5-35377
Quantity :
100 uL
Price :
US 470.00
Clonality :
Polyclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rabbit, Rat
Applications :
Immunohistochemistry: 1:1,000, Immunoprecipitation: 3 uL / 200 ug lysate, Western Blot: 1:1,000
Species :
Human, Mouse, Rabbit, Rat
Isotype :
IgG
Storage :
-20 C
Description :
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen :
Fusion protein from the C-terminal region of the NR2A subunit of rat GRIN2A
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry: 1:1,000, Immunoprecipitation: 3 uL / 200 ug lysate, Western Blot: 1:1,000
Aliases :
EPND; FESD; GluN2A; GluRepsilon1; glutamate [NMDA] receptor subunit epsilon-1; glutamate ionotropic receptor NMDA type subunit 2A; glutamate receptor; glutamate receptor ionotropic, NMDA 2A; glutamate receptor, ionotropic, NMDA2A (epsilon 1); glutamate receptor, ionotropic, N-methyl D-aspartate 2A; Grin2a; hNR2A; LKS; NMDA Receptor 2A; NMDAR 2A; NMDAR2A; N-methyl D-aspartate receptor subtype 2A; N-methyl-D-aspartate receptor channel, subunit epsilon-1; N-methyl-D-aspartate receptor subunit 2A; NR2A; OTTHUMP00000160135; OTTHUMP00000174531
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA