CRMP1 Polyclonal Antibody | Invitrogen PA5-34768 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CRMP1 Polyclonal Antibody

catalog :

PA5-34768

quantity :

100 uL

price :

US 522.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 3

Reference
Chang J, Chou C, Wu J, Liao K, Luo W, Hsu W, et al. LCRMP-1 is required for spermatogenesis and stabilises spermatid F-actin organization via the PI3K-Akt pathway. Commun Biol. 2023;6:389 pubmed publisher
Hagemann C, Moreno Gonzalez C, Guetta L, Tyzack G, Chiappini C, Legati A, et al. Axonal Length Determines Distinct Homeostatic Phenotypes in Human iPSC Derived Motor Neurons on a Bioengineered Platform. Adv Healthc Mater. 2022;11:e2101817 pubmed publisher
Marini C, Cossu V, Bonifacino T, Bauckneht M, Torazza C, Bruno S, et al. Mechanisms underlying the predictive power of high skeletal muscle uptake of FDG in amyotrophic lateral sclerosis. EJNMMI Res. 2020;10:76 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CRMP1 Polyclonal Antibody

Catalog # :

PA5-34768

Quantity :

100 uL

Price :

US 522.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:200, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:1,000-1:50,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis. Their continued expression in areas of high synaptic remodeling such as the cerebellum, hippocampus, and the olfactory system suggests that these proteins may also be involved in adult brain plasticity. CRMP-1 was initially identified as a dihydro-pyrimidinase expressed exclusively in brain; later studies have shown that it is involved with neurotrophin (NT) 3-induced neurite formation and outgrowth. CRMP-1 localization switches from axonal to somatodendritic when neurons reach functional maturity, suggesting that it is involved in early neuronal differentiation as well as in later processes related to the survival or death of the newly generated neurons.

Immunogen :

Recombinant fragment corresponding to a region within amino acids 34 and 305 of CRMP1 (Uniprot ID#Q14194)

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:200, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:1,000-1:50,000

Aliases :

Collapsin response mediator protein 1; Crmp1; CRMP-1; dihydropyrimidinase-like 1; dihydropyrimidinase-related protein 1; Dpysl1; DRP1; DRP-1; Ulip3; ULIP-3; Unc-33-like phosphoprotein 3