IFITM3 Polyclonal Antibody | Invitrogen PA5-34598 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IFITM3 Polyclonal Antibody

catalog :

PA5-34598

quantity :

100 ug

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section

citations: 3

Reference
Wang J, Fang J, Feng M, Li L, Ma L, Zhao X, et al. Inhibition of EED activity enhances cell survival of female germline stem cell and improves the oocytes production during oogenesis in vitro. Open Biol. 2023;13:220211 pubmed publisher
Wang J, Du H, Ma L, Feng M, Li L, Zhao X, et al. MitoQ Protects Ovarian Organoids against Oxidative Stress during Oogenesis and Folliculogenesis In Vitro. Int J Mol Sci. 2023;24: pubmed publisher
Zhang X, Yang Y, Xia Q, Song H, Wei R, Wang J, et al. Cadherin 22 participates in the self-renewal of mouse female germ line stem cells via interaction with JAK2 and β-catenin. Cell Mol Life Sci. 2018;75:1241-1253 pubmed publisher

product information

Product Type :

Antibody

Product Name :

IFITM3 Polyclonal Antibody

Catalog # :

PA5-34598

Quantity :

100 ug

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Mouse, Rat

Applications :

Immunocytochemistry: 5-10 ug/mL, Immunohistochemistry (Frozen): 10 ug/mL, Immunoprecipitation: Assay-Dependent, Western Blot: 0.25-1 ug/mL

Species :

Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

IFITM3 (interferon induced transmembrane protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein that belongs to the IFITM (interferon inducible transmembrane) family of proteins. IFITM proteins are induced by type I and type II interferons and contain multiple interferon (IFN)-stimulated response elements (ISREs) in their promoter regions. IFITM proteins play important roles in many cellular processes and their expression requires the presence of the chromatin remodeling SWI/SNF-like BAF complexes. Cellular processes involving IFITM proteins include cellular anti-proliferative activities and homotypic cell adhesion functions of interferons. In addition, IFITM genes are often upregulated in various cancer cells, suggesting a possible role in carcinogenesis. Localizing to the membrane, IFITM3 is a 133 amino acid protein that is induced by IFN-alpha and IFN-gamma. IFITM3 expression can be regulated by TEF-1, Brg-1 and Sp1.

Immunogen :

Synthetic peptide derived from residues 1 - 50 of Mouse Fragilis.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 5-10 ug/mL, Immunohistochemistry (Frozen): 10 ug/mL, Immunoprecipitation: Assay-Dependent, Western Blot: 0.25-1 ug/mL

Aliases :

1110004C05Rik; 1-8U; Cd225; Cdw217; Dispanin subfamily A member 2b; DSPA2b; Fgls; Fragilis; Fragilis 3; Fragilis protein; Ifitm3; ifitm-like protein 1; interferon induced transmembrane protein 3; interferon-induced transmembrane protein 3; interferon-inducible protein 15; Interferon-inducible protein 1-8U; interferon-inducible protein variant 10; IP15; mil-1; Mouse ifitm-like protein 1; rat8