IL17RA Polyclonal Antibody | Invitrogen PA5-34571 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IL17RA Polyclonal Antibody

catalog :

PA5-34571

quantity :

100 ug

price :

US 474.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

citations: 2

Reference
Brabec T, Vobo x159 il M, Schierov xe1 D, Valter E, x160 pl xed chalov xe1 I, Dobe x161 J, et al. IL-17-driven induction of Paneth cell antimicrobial functions protects the host from microbiota dysbiosis and inflammation in the ileum. Mucosal Immunol. 2023;16:373-385 pubmed publisher
Jung B, Samten B, Dean K, Wallace R, Brown Elliott B, Tucker T, et al. Early IL-17A production helps establish Mycobacterium intracellulare infection in mice. PLoS Pathog. 2022;18:e1010454 pubmed publisher

product information

Product Type :

Antibody

Product Name :

IL17RA Polyclonal Antibody

Catalog # :

PA5-34571

Quantity :

100 ug

Price :

US 474.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry: 2.5 ug/mL, Western Blot: 1 ug/ml

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

4 C

Description :

Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F. IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections.

Immunogen :

An 18 amino acid peptide near the amino terminus of human IL-17RA

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: 2.5 ug/mL, Western Blot: 1 ug/ml

Aliases :

AW538159; CANDF5; CD127; CD217; CDw217; hIL-17R; IL-17 receptor A; IL17R; Il17ra; IL-17RA; interleukin 17 receptor A; interleukin-17 receptor A; MGC10262; VDw217