CMPK2 Polyclonal Antibody | Invitrogen PA5-34461 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CMPK2 Polyclonal Antibody

catalog :

PA5-34461

quantity :

100 ug

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

citations: 2

Reference
Sun Z, You T, Zhang B, Liu Y, Liu J. Bone marrow mesenchymal stem cell-derived exosomes miR-202-5p inhibited pyroptosis to alleviate lung ischemic-reperfusion injury by targeting CMPK2. Kaohsiung J Med Sci. 2023;39:688-698 pubmed publisher
Chen Y, Wu L, Shi M, Zeng D, Hu R, Wu X, et al. Electroacupuncture Inhibits NLRP3 Activation by Regulating CMPK2 After Spinal Cord Injury. Front Immunol. 2022;13:788556 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CMPK2 Polyclonal Antibody

Catalog # :

PA5-34461

Quantity :

100 ug

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry: 20 ug/mL, Western Blot: 1 ug/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Maintain refrigerated at 2-8 C for up to 3 months. For long term storage store at -20 C

Description :

UMP-CMP kinase 2 (CMPK2) is the first nucleoside monophosphate kinase that has been identified in human mitochondria. It is a component of the salvage pathway for nucleotide synthesis that may participate in terminal differentiation of monocytic cells. There are two distinct domains of CMPK2: the N-terminal domain with unknown function and the C-terminal domain with the kinase function, suggesting that CMPK2 may be a bifunctional protein with other biological functions in addition to its UMP-CMP kinase activity. CMPK2 may participate in dUTP and dCTP synthesis and is responsible for phosphorylation of dCMP and dUMP in mitochondria. CMPK2 is actively involved in macrophage activation and the inflammatory response.

Immunogen :

A 19 amino acid synthetic peptide near the carboxy terminus of human CMPK2

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: 20 ug/mL, Western Blot: 1 ug/mL

Aliases :

1200004E04Rik; Cmpk2; cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial; cytidine/uridine monophosphate kinase 2; cytidylate kinase 2; mitochondrial UMP-CMP kinase; NDK; Nucleoside-diphosphate kinase; TDKI; thymidine monophosphate kinase 2; thymidylate kinase family LPS-inducible member; thymidylate kinase homologue; thymidylate kinase LPS-inducible member; TMPK2; Tyki; UMP/CMP kinase; UMP-CMP kinase 2, mitochondrial; UMP-CMPK2