This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
FOXRED2 Polyclonal Antibody
catalog :
PA5-34345
quantity :
100 ug
price :
US 474.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunocytochemistry
product information
Product Type :
Antibody
Product Name :
FOXRED2 Polyclonal Antibody
Catalog # :
PA5-34345
Quantity :
100 ug
Price :
US 474.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human
Applications :
Immunocytochemistry: 20 ug/mL, Western Blot: 1 ug/mL
Species :
Human
Isotype :
IgG
Storage :
Maintain refrigerated at 2-8 C for up to 3 months. For long term storage store at -20 C
Description :
FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D.
Immunogen :
A 17 amino acid synthetic peptide near the amino terminus of human FOXRED2
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 20 ug/mL, Western Blot: 1 ug/mL
Aliases :
Endoplasmic reticulum flavoprotein associated with degradation; ER flavoprotein associated with degradation; ERFAD; FAD dependent oxidoreductase domain containing 2; FAD-dependent oxidoreductase domain containing 2; FAD-dependent oxidoreductase domain-containing protein 2; FOXRED2
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA