EAR2 Polyclonal Antibody | Invitrogen PA5-34008 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

EAR2 Polyclonal Antibody

catalog :

PA5-34008

quantity :

50 ug

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

Chinese hamsters, human, mouse, rat, dogs, bovine, pigs , zebrafish

application :

immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

EAR2 Polyclonal Antibody

Catalog # :

PA5-34008

Quantity :

50 ug

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Bat, Bovine, Canine, Hamster, Human, Mouse, Non-human primate, Porcine, Rat, Xenopus laevis, Zebrafish

Applications :

Immunohistochemistry (Paraffin): 5 ug/mL

Species :

Bat, Bovine, Canine, Hamster, Human, Mouse, Non-human primate, Porcine, Rat, Xenopus laevis, Zebrafish

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type-specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4(+) T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. Involved in development of forebrain circadian clock; is required early in the development of the locus coeruleus (LC).

Immunogen :

Synthetic 16 amino acid peptide from ligand-binding domain of human NR2F6.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 5 ug/mL

Aliases :

AV090102; avian erythroblastic leukemia viral (v-erb-a) oncogene homolog-like 2; COUP transcription factor 3; COUPg; COUP-TF3; EAR2; EAR-2; Erba related 2; ERBAL2; ERBA-related gene-2; Nr2f6; Nuclear receptor subfamily 2 group F member 6; nuclear receptor subfamily 2, group F, member 6; nuclear receptor V-erbA-related; orphan nuclear receptor EAR-2; Ovalbumin upstream promoter gamma nuclear receptor; ovalbumin upstream promoter gamma nuclear receptor rCOUPg; v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 2; V-erbA-related protein 2; V-erbA-related protein EAR-2