KCNMA1 Polyclonal Antibody | Invitrogen PA5-33872 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

KCNMA1 Polyclonal Antibody

catalog :

PA5-33872

quantity :

50 ug

price :

US 474.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

Chinese hamsters, human, mouse, rat, chicken, bovine, pigs , zebrafish , domestic rabbit, domestic horse

application :

immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

KCNMA1 Polyclonal Antibody

Catalog # :

PA5-33872

Quantity :

50 ug

Price :

US 474.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Bovine, Chicken, Equine, Hamster, Human, Mouse, Non-human primate, Porcine, Rabbit, Rat, Xenopus laevis, Zebrafish

Applications :

Immunohistochemistry (Paraffin): 10-20 ug/mL

Species :

Bovine, Chicken, Equine, Hamster, Human, Mouse, Non-human primate, Porcine, Rabbit, Rat, Xenopus laevis, Zebrafish

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open.

Immunogen :

Synthetic 15 amino acid peptide from internal region of human KCNMA1.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 10-20 ug/mL

Aliases :

5730414M22Rik; bA205K10.1; big potassium channel alpha subunit; BK channel; BK channel alpha subunit; BKCa; BKCA alpha; BKCA alpha subunit; BKTM; calcium-activated potassium channel alpha subunit; calcium-activated potassium channel subunit alpha-1; calcium-activated potassium channel subunit alpha-1; uncharacterized protein; calcium-activated potassium channel, subfamily M subunit alpha-1; hSlo; K(VCA)alpha; KCa1.1; Kcnma; Kcnma1; KCNMA1b; KCNMA1c; Maxi K channel; maxiK; maxi-K channel HSLO; mSlo; mSlo1; potassium calcium-activated channel subfamily M alpha 1; potassium channel, calcium activated large conductance subfamily M alpha, member 1; potassium large conductance calcium-activated channel, subfamily M, alpha member 1; SAKCA; SLO; slo homolog; slo1; Slo-alpha; Slowpoke homolog; stretch-activated Kca channel