This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
GPR26 Polyclonal Antibody
catalog :
PA5-33683
quantity :
50 ug
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, dogs, pigs , domestic horse
application :
immunohistochemistry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
GPR26 Polyclonal Antibody
Catalog # :
PA5-33683
Quantity :
50 ug
Price :
US 464.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Canine, Equine, Human, Non-human primate, Porcine
Applications :
Immunohistochemistry (Paraffin): 6-15 ug/mL
Species :
Canine, Equine, Human, Non-human primate, Porcine
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR26 is a brain-specific orphan GPCR with a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. In the CNS, the highest GPR26 expression is in the amygdala, hippocampus and thalamus. Weak expression is detected in testis. GPR26 is down-regulated in glioblastoma. Depletion of GPR26 has been shown to increase fat storage in C. elegans, whereas GPR26 deficiency in the hypothalamus is associated with high genetic susceptibility to the onset of obesity in mice. GPR26 deficiency also causes metabolic complications commonly associated with obesity, including glucose intolerance, hyperinsulinemia, and dyslipidemia.
Immunogen :
Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human GPR26.
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 6-15 ug/mL
Aliases :
9630036A11Rik; A730021D22; DKFZp761H2121; FLJ33774; G protein-coupled receptor 26; Gpr26; G-protein coupled receptor 26; MGC138216; probable G-protein coupled receptor 26
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA